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Metzger J.V. — Thiazole and Its derivatives (Part 2)
Metzger J.V. — Thiazole and Its derivatives (Part 2)



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Название: Thiazole and Its derivatives (Part 2)

Автор: Metzger J.V.

Аннотация:

General introduction to protomeric thiazoles; aminothiazoles and their derivatives; and mercaptothiazoles, hydroxythiazoles, and their derivatives


Язык: en

Рубрика: Химия/

Статус предметного указателя: Готов указатель с номерами страниц

ed2k: ed2k stats

Год издания: 1979

Количество страниц: 590

Добавлена в каталог: 21.09.2006

Операции: Положить на полку | Скопировать ссылку для форума | Скопировать ID
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Предметный указатель
Ambident reactivity of $\Delta$-4-thiazoline-2-one anion, examples      401
Ambident reactivity of $\Delta$-4-thiazoline-2-thione anion      394
Ambident reactivity of $\Delta$-4-thiazoline-2-thione anion, in relation with HSAB classification      397
Ambident reactivity of $\Delta$-4-thiazoline-2-thione anion, in relation with Klopman — Hudson approach      397
Ambident reactivity of $\Delta$-4-thiazoline-2-thione anion, steric effect on      394
Ambident reactivity of hydrazinothiazoles      100
Ambident reactivity of nucleophilic species      68
Ambident reactivity of rhodanine      419
Ambident reactivity of sulfathiazoles      116 117
Ambident reactivity, and Edwards equation      5
Ambident reactivity, general features      61
Ambident reactivity, in alkylations, by alcohols      38 39
Ambident reactivity, in alkylations, of acetamidothiazoles      37
Ambident reactivity, in alkylations, of anions      36 37
Ambident reactivity, in alkylations, of nitraminothiazoles      37
Ambident reactivity, in alkylations, of sulfathiazole      37
Ambident reactivity, of 2-aminothiazoles      30
Ambident reactivity, of electrophilic centers      31 39 126
Ambident reactivity, of electrophilic centers, in new heterocyclic synthesis      33
Ambident reactivity, of electrophilic centers, toward ambident nucleophiles      61
Ambilhar      138 145
Amebicidal      141
Amide ions, alkylaminothiazoles      34
Amide ions, from 2-aminothiazoles      35
Amides, amide-imide tautomerism      116
Amides, with 2-aminothiazoles      47
Amines      403
Amines in chemical structure determination      37
Amines, nitrosation of secondary      40
Amines, preparation of secondary and tertiary      13
Amines, reaction on, 2-alkylthio-$\Delta$-2 thiazoline-4- one      424
Amines, reaction on, 2-benzylthio-oxo-$\Delta$-2-thiazoline-5-one      433
Amines, reaction on, 2-chloro-$\Delta$2-thiazoline-4-one      424
Amines, reaction on, 2-thiazolylsulfonic acid      414
Aminium salts, acylation reagent      132
Aminium salts, alkoxycarbonylation reagent      132
Amino acids, in synthesis of $\Delta$-2-thiazoline-5-ones      426
Amino acids, reaction on 4-substituted-2-phenyl-$\Delta$-2-thiazoline-5-ones      433
Amino-imino equilibrium, and $pK_a$      19
Amino-imino equilibrium, and activation of reactivity      18
Amino-imino equilibrium, and HMO treatment      17 19 20 100
Amino-imino equilibrium, and IR      23
Amino-imino equilibrium, and NMR      25
Amino-imino equilibrium, and potentiometry      21
Amino-imino equilibrium, and UV      19 20.
Amino-imino equilibrium, for excited states      21
Amino-imino equilibrium, molecular orbital calculations of      17
Aminoalkylation, of 2-aminothiazoles      81
Aminoalkylation, of acetaminotfuazoles      44
Aminopyridine, and ambident reactivity      63
Aminopyridine, and HSAB      63
Aminopyridine, bromination of      79
Aminopyridine, by Chichibabin reaction      12
Aminopyridine, diazotization of      67
Aminopyridine, nitration of      72
Aminothiazoie-N-oxide      118
Ammonia      115
Ammonia towards radical anion      87
Ammonia with sodium      86
Ammonium chloride, catalysis by      56
Ammonolysis of 2-halothiazoles      12
Amyl nitrite, deamination by      112
Analgesic activity      144 145 147 438 440 442
Analytical uses      30 153 156—168
Analytical uses of azothiazoles      107 154
Analytical uses of chelates      95
Anesthetic activity      42 43 145 149
Angina, treatment of      439
Anhydrides, to acylaminothiazoles      90
Anhydrides, with 2-aminothiazoles      47
Anhydrides, with sulfa thiazoles      117
Aniline, by hydrolysis      130
Aniline, rearrangements in      70 83
Aniline, to 4-aminothiazoles      16
Anions, ambident reactivity of      36
Anions, from thiazolylureas      93
Anions, in 2-aminothiazoles alkylation      34
Anions, of 2-imino-4-thiazoline      127
Anorectic      147
Anthelmintic activity      126 137 430 440 441
Antiamebic activity, of 5-nitro-2-aminothiazoles      72
Antiarrhythmics      441
Antibacterial      see Bactericide
Anticholesteremic      150
Anticonvulsant      438
Antifoggant      438
Antifungal agent      139. See also Fungicides
Antihistaminic agent      149
Antihistomonal activity, of 5-nitro-2-aminothiazoles      72
Antiinfective agent      148
Antiinflammatory      138 144 145 438 440 442
Antilipemic      150
Antimalarial agent      140
Antimicrobial      138 141
Antimimotic      152
Antimonytrichloride, with azothiazoles      111
Antimutagenic activity      152
Antineoplastics      76
Antioxidant      170 438
Antiparasitic      136 137.
Antiphlogistic      440 442
Antiprotozoan agent      139
Antipyretic activity      144 145 147 148 440 442
Antischistosomal activity, of 5-nitro-2-aminothiazoles      72
Antispasmodic activity      150 439
Antitrichomonal activity      138
Antitrichomonal activity of 5-nitio-2-aminothiazoles      72
Antitubercular activity      139 140 441 442
Antitumor activity      149 152
Antitussive      144 148
Antiulcer properties      148
Antiviral      138 139 140 144 438
Appetite depressant      147
Aprotic solvent      see Solvent effect
Aromatic aldehydes, with aminothiazoles      40
Aryl amines      403
Aryl diazonium salts, $\Delta$-2-thiazoline-4-ones      425
Aryl diazonium salts, reaction with, rho-danine      419
Aryl halides, $\Delta$-4-thiazoline-2-thione anion      396
Aryl halides, with 2-hydrazinothiazples      101
Aryl nitroso, reaction with, $\Delta$-2-thiazoline-4-one      425
Arylsulfenyl chlorides, with 2-aminothiazoles      69 113
Arylsulfonyl halides      98 115
Arylsulfonylbenzimidoyl chlorides, with aminothiazoles      50
Azide, Curtius rearrangement of      15 16.See
Azide, to carbamate      16
Azide, with azothiazoles      111
Azido thiazoles      113
Azido thiazoles, azidothiazole-thiazolotetrazole      113
Azido thiazoles, reactions of      113
Azirines, reaction with isothiocyanates      15
Azo dye      156—168. See also Dyes
Azothiazoles      105 153 170 271—274
Azothiazoles, $pK_a$ of      107
Azothiazoles, analytical applications      107
Azothiazoles, by diazo coupling      105
Azothiazoles, by oxidation      102 105
Azothiazoles, dyes      107
Azothiazoles, IR spectra of      107
Azothiazoles, NMR data of      105
Azothiazoles, paper electrophoretic      107
Azothiazoles, polarography of      108
Azothiazoles, protomeric equilibrium with      107
Azothiazoles, X-Ray data      107
Bacteria leaf blight      136
Bactericide      134 136 137 138 139 140 438 439 441 442
Bacteriostatic properties      139 152
Bacterium citri, control of      441
Barium thiocyanate      118
Barrier to rotation, around $Nsp^2$-$Csp^3$ bond, in 3,4-diisopropyl-$\Delta$4-thiazoline-2-one      390
Barrier to rotation, around $Nsp^2$-$Csp^3$ bond, in N-2-propanoic, $\Delta$4-thiazoline-2-thione      387
Barrier to rotation, around $Nsp^2$-$Csp^3$ bond, in N-alkyl, $\Delta$-4-thiazoline-2-thione      387
Base catalysis      34
Base catalysis in acylations      47 48
Base catalysis in hydrolysis      115
Base catalysis of chelate formation      95
Base catalysis of clevage      128
Base catalysis of cy clization      127
Basicity, of 2-aminothiazole      90
Basicity, of 2-imino-4-thiazolines      124
Beckmann rearrangement, of oxime      16
Benzaldehyde, with $\Delta$-2-thiazoline-4-ones      425
Benzaldehyde, with alkyl-acetamidothiazole      46
Benzaldehyde, with aminothiazoles      47
Benzaldehyde, with diaminothiazoles      47
Benzaldehyde, with hydrazinothiazoles      100
Benzamide, with 2-bromothiazole      48
Benzene derivatives, coupling with      112
Benzene derivatives, nitrarhino      113
Benzene derivatives, polarographic behavior of      107
Benzhydryl chloride      431
Benzhydryl chloride with 2-aminothiazole      34
Benzidine-like rearrangement      104
Benzimidazole derivatives      57
Benzoin, reaction with, $S_8$,      373
Benzoselenazolium salts, reaction of with $\Delta$-2-thiazoline-4-one      425
Benzothiazoline-2-thione (N-Me), methylation of      391
Benzothiazolium salts, reaction of, with $\Delta$-2-thiazoline-4-one      425
Benzoyl chloride      431
Benzoyl chloride with 2-aminothiazoles      48
Benzyl bromide, with thiazolylthiourea      95
Benzyl chloride, with aminothiazoles      33 80
Benzylidene bis aminothiazoles      41
Bidentate ligands      120
Biheterocycles      99. See also Condensed heterocycles
Biological activity      138
Biological activity, 2-aminothiazoles in samples      30
Biological processes      85
Bioluminescence, of firefly lanterns      420
Birch reduction      398
Bisheterocycles      45 46 55 102 104 105 372 373 402 404 408 427 437.
Bismuth complexes      156—168
Biuret, from 2-aminothiazoles      56
Black head in turkeys      148
Blood, 2-aminothiazole in      30
Blood, pharmaceutical use      148
Bromination, of $\Delta$-4-thiazoline-2 one      402
Bromination, of 2-acetamidothiazoles      79
Bromination, of 2-acetyliminothiazolines      128
Bromination, of 2-aminothiazoles      78 79
Bromination, of 2-azidothiazoles      113
Bromination, of 2-hydrazinothiazoles      103 106
Bromination, of 2-thiazolyl-sulfone      415
Bromination, of 5-thiazolyl-oxide      436
Bromination, with bromine      77
Bromination, with N-bromosuccinimide      77
Bromothiazole, in Ullman synthesis      115
Bromothiazole, with benzamide      48
Bromothiazole, with hydrazine      99
Brown root      138
Burmistrov method      128
Butylglycidylether, with azothiazoles      108
Cadmium complexes      104 156—168
Carbamates      241 242
Carbamates from azides      16
Carbamates from ethyl chloroformate      51. See also Thiazolyl carbamates
Carbamates with acetic anhydride      16
Carbamoyl chloride      431
Carbene intermediates      376 377
Carbinol      see Alcohol
Carbinolamine intermediate      41
Carbocations      47
Carbocations from alcohols      39
Carbocations from diazoniums      108
Carbocations in acidic alkylations of aminothiazoles      38
Carbocations in F-C alkylations      80
Carbocations in nitrations      85
Carbon disulfide      60
Carbon disulfide in chemical structure determination      37
Carbon disulfide with 2-aminothiazole      60 94
Carbon disulfide with 2-iminothiazole      371
Carbon disulfide with 3-amino-2-iminothiazoline      131
Carbon disulfide with propargylamine      372
Carbonyl derivatives      40
Carbonyl derivatives with 2-aminopyridine      54
Carbonyl derivatives with aminothiazoles      40 54
Carboxylic acids      see Acid (carboxylic)
Carcinolytic      152 153
Cardiovascular agent      138 441
Catalysis, by ammonium chloride      56
Catalysis, by diketones      53
Catalysis, by imidazole - $PPh_3$, mixture      90
Catalysis, by nickel      116
Catalysis, by tin      116. See also Acid catalysis; Base catalysis
Catalysis, enzymatic      77
Catalysis, of acylation      53
Cationic dyes      105
Cellulose acetate      105
Cephalosporin structure      138
Charge control reactivity      118
Charge diagram, $\Delta$-4-thiazoline-2-one      389 403
Charge diagram, $\Delta$-4-thiazoline-2-thione      389
Charge diagram, 2-hydroxythiazole      390
Charge diagram, 2-mercaptothiazole      390
Charge transfer, and U.V. spectra      21
Chelates, with metal ions      95
Chemical identification, of quaternarized aminothiazoles      37
Chemical identification, of sulfonyl thiazoles      75
Chemiluminescence, of firefly lanterns      421
Chemotherapeutic activity      152
Chichibabin reaction      12
Chichibabin reaction in synthesis of 2-aminothiazole      12
Chloraceiic acid, alkylation with      33
Chloraceiic acid, dialkylation with      37
Chloraceiyl chloride, with aminothiazoles      49
Chloracetic anhydride      124
Chloracetic ester, alkylation with      33
Chloride anion      121
Chlorination, by $SOCl_2$      77
Chlorination, by HCl      77
Chlorination, of $\Delta$-2-thiazoline-5-one      432
Chlorination, of $\Delta$-4-thiazoljne-2-one      402
Chlormethiazole, metabolism of      375
Chlorodiethylphosphate, reaction with, $\Delta$-4-thiazolme-2-one      401
Chlorodiethylthiophosphate, reaction with, $\Delta$-4-thiazoline-2-one      401
Chlorooxime      118
Chloroplatmate anion      121
Chlorothiazole, with $\beta$-hydroxyethylamine      34
Chlorothiazole, with 2-imiro-4-thiazoline      57
Chlorothioformic phenyl ester, with 2-aminothiazoles      51
Chlorovinyl ketones, with 4-aminothiazoles      46
Chrysean, complexes with      122
Chrysean, synthesis of      16
CINDP      83
Circular dichroism, $\Delta$-4-thiazoline-2-thione      380
cis-isomers      120
Claisen rearrangements, in 2-allyloxythiazole, kinetic siudy      410
Claisen rearrangements, stereochemistry      410
Cleavage, of 2-acetylimino-4-thiazolines      128
Cleavage, of aryl sulfonamidothiazole      117
CNDO calculations, $\Delta$-4-thiazoline-thione-2, electronic transitions      380
CNDO calculations, $\Delta$-4-thiazoline-thione-2, PES spectra      381
CNDO calculations, charge diagram and PES spectra      17 18
Cobalt, complexes of      70 99 104 107 156 158 160 161
Coccidiostatic      152
Coding structures      139
Color-coupling agents      159
Colorimetry, in sulfathiazole determination      116
Complexes      57 99 70 104 107 108 119 120 122 154 156—168
Condensed heterocycles      33 34 42 43 44 45 49 50 53 54 56 57 58 60 62 65 69 78 95 96 130
1 2 3 4 5 6 7 8 9
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