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Hodgson E. — A Textbook of Modern Toxicology
Hodgson E. — A Textbook of Modern Toxicology



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Название: A Textbook of Modern Toxicology

Автор: Hodgson E.

Аннотация:

Hodgson (toxicology, North Carolina State University) provides an accessible overview of toxicology, suitable for junior and senior undergraduate courses in environmental, pharmacological, medical, and veterinary toxicology. The text emphasizes the biochemical aspects of toxicology at the cellular and molecular levels, and readers are assumed to have some background in chemistry, biochemistry, and animal physiology. In this third edition, new contributors describe the latest work in their respective areas of specialization and discuss emerging topics such as molecular biological aspects of technology. A glossary and a summary section are included.


Язык: en

Рубрика: Медицина и здравоохранение/

Статус предметного указателя: Готов указатель с номерами страниц

ed2k: ed2k stats

Издание: Third edition

Год издания: 2004

Количество страниц: 582

Добавлена в каталог: 12.05.2005

Операции: Положить на полку | Скопировать ссылку для форума | Скопировать ID
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Предметный указатель
$\beta$-Lyase      145 277 278
$\gamma$-Aminobutyric acid      222
1,2-Epoxy-3-(p-nitrophenoxy) propane      144
1,3-Butadiene      122
1-Aminobenzotriazole      185
1-Chloro-2,4-dinitrobenzene      144
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)      129 286 290 297
1-Naphthalene methyl sulfate      144
1-Naphthol      138
12-O-Tetradecanoyl phorpol-13-acetate      239 242
2,4-Dinitrophenol      224
2,4-Dinitrophenol, and cataracts      174
2,6-Dichlorobenzonitrile      122
2-Aminofluorene      129
2-Butanol      140
2-Naphthamine      138
3'-Phosphoadenosine-5'-phosphosulfate (PAPS)      140
4-Aminobiphenyl      121
4-Nitrophenol      140
5-Aza-2-deoxycytine      345
6-Methylthiopurine      125
A-Esterase      see Esterase
Absorption      77—110
Absorption, dermal      91—94
Absorption, gastrointestinal      89—91
Absorption, respiratory      94—97
Acceptable daily intake      427 525 538
Acetaminophen      123 140 154 158 160 265 271 272 274
Acetylaminofluorene      121 122 125 126 157 158 175 265 268
Acetylation      146 525
Acetylator phenotype      525
Acetylcholine      220 221
Acetylcholinesterase      60 155 290 291 296
Acetylesterase      220 221
Acetylsalicylic acid      see Aspirin
Acid deposition      39 525
ACR      see Acute to chronic ratio
Actinomycin A      223
Actinomycin D      345
Action potential      281 287
Activation      149 150 152 243 274 525
Active oxygen      525
Acutane      256
Acute to chronic ratio      473
Acute toxicity      see Toxicity
Acylation      145 146
Acyltransferase      146
Adaptation, to toxicants      182 526 538
ADI      see Acceptable daily intake
Adjuvants      339—341
Administration of toxicants      4
Adrenals      171 300
Adrenocorticotropic hormone, metabolic effects      171
Advection      483—485
Aflatoxin      121 122—124 152 156 237—238 248 265
Aflatoxin dihydrodiol      156
Agonist      306 308 309
Agricultural chemicals      7 54—64
Ah locus      526
Ah receptor      see Arylhydrocarbon receptor
Air pollution      33 331 338—341 419 526
Airways      317
Albumin      311
Alcohol dehydrogenase      112 130 155 186
Alcohols      220
Aldehyde dehydrogenase      112 130 155
Aldehyde reduction      134
Aldrin      112 124
Algal toxins      67
Aliphatic epoxidation      124
Aliphatic hydroxylation      112 124
Alkylating agents      526
Allergens, food      341
Allergens, respiratory      338
Allergic contact dermatitis      337—338
Allergic response      321
Allergy      336—341
Allyl alcohol      265
Allylisopropylacetamide      185 189
Altitude, metabolic effects      200
Aluminum      318
Alveolar ducts      317
Alveoli      317
American conference of governmental industrial hygienists      418
Ames test      249 385 526
Amidase      112 135 175
Amine oxidase      131
Amines      220
Amino acid conjugation      147
Aminoglycosides      276
Amitryptline      265
Ammonia      318
Amphetamine      126
Analytical methods files      25
Androgen receptor      see Receptors
Androgens      119 300
Aneuploidy      245
Aniline hydroxylation      174 175
Animal husbandry, in toxicity testing      365—366
Antagonism      190 527
Antagonist      308 309
Antibodies, definition      527
Antibodies, inhibitory      21
Antibodies, monoclonal      19—20
Antibodies, polyclonal      19—20
Antibody-forming cell assay      331—332
Antidote      527
Antimony      181
Antipyrine metabolism      186
Apoptosis      227 241—242 245 248 266
Arachidonic acid      122 132
Aromatic hydroxylation      112 123
Arsenic      41 44 53 318 408
Artemisinin      122
Arylesterases      135
Arylhydrocarbon receptor (Ah receptor)      121 192 526
Arylhydroxamic acid      147
Asbestos      46 47 318
Asbestosis      318
Aspirin      4
Asthma      338—339
Astrocyte      281 284 290
ATP synthetase      223
Atrazine      464 467 474 482
Auditory startle      383
Autoimmune disease      327 336 341
Autonomic      280—291
Avermectin      222
Avian testing      394
Axon      280 281 285—286 287—288
Axonal transport      285—286
Azaserine      265
Azide      223
Azo reduction      112 133 180
B lymphocytes      see Lymphocytes B
B-Esterase      see Esterase
Barbie box      194
Behavioral toxicity      see Toxicity
Belladonna      4 173
Benchmark dose      430
benzene      46 47 123
Benzidine      121 146
Benzo(a)pyrene      237 243—245 248 322
Benzo(a)pyrene, activation      158
Benzo(a)pyrene, metabolism      159
Benzoic acid      146
Benzoperylene      464
Beryllium      265 318
Bile canaliculi      208 209 263
Bile duct      263 207 209
Bilirubin      139
Binding, covalent      see Covalent binding
Bioaccumulation      467 468 469 470 472 527
Bioactivation      see Activation
Bioassay      527
Bioavailability      77
Biochemical methods, in toxicology      13—22
Bioconcentration      488 see
Biomagnification      467 see
Biomethylation, of elements      142
Bioremediation      465
Biotransformation      495
Blastocyst      253
Blending      447
Blood coagulation      300
Blood urea nitrogen (BUN)      274
Bluegill      394
Bobwhite quail      394
Bone density      300
Botanical insectidicides      60—61
Botulinum toxin      292
Bowman’s capsule      206
Bromobenzene      265 270
Bromobenzene metabolites      271 272 274
Bronchi      317
Bronchioles      317
Bronchitis      318
BUN      see Blood urea nitrogen
Bupropion      122
Burden of proof      527
C-Esterase      see Esterase
Cadmium      41 46 51 52 275 318
Calcium homeostasis      266
Cancer, incidence and mortality      228—231
Cancer, lung      318 321 322
Cancer, nasal      318
Cancer, process      225—227
Cancer, susceptibility      229—230
Capillary electrophoresis      454
CAR      see Constitutive active receptor
Carbamate(s)      20 60 221 408 471 477
Carbaryl      123 473
Carbasone      265
Carbofuran      464
Carbohydrates, metabolic effects      164
Carbon monoxide      36
Carbon monoxide, spectrum      114
Carbon tetrachloride      4 123 153 156 173 189 265 269 274
Carbophenothion sulfoxide      134
Carboxylesterase      135
Carcinogen(s)      3 121 528
Carcinogen(s), classification of human carcinogens      233—237
Carcinogen(s), direct-acting      237
Carcinogen(s), epigenetic      239—240 528
Carcinogen(s), genotoxic      237—238 528
Carcinogen(s), indirect-acting      237
Carcinogen(s), known human      233—235
Carcinogen(s), parent      240
Carcinogen(s), procarcinogen      150
Carcinogen(s), proximate      150 240 528
Carcinogen(s), ultimate      150 240 528
Carcinogenesis      6 225—250 267 528
Carcinogenesis, rodent bioassay      233—234
Carcinogenesis, testing      371—378
Carson, Rachel      9
Catechol O-methyltransferase      142
Cell culture, cell lines      15
Cell culture, induction, in cultured cells      15
Cell culture, monolayer      14
Cell culture, suspension      14
Cell culture, techniques      13—16
Cell culture, toxicity, in cultured cells      14—16
Cell membrane      16 78—80
Cell transformation test      392
Cellular methods, in toxicology      13—22
Cellular respiration, inhibition      223
Central nervous system (CNS)      279—280 379
CERCLA      see Comprehensive environmental response compensation
Checkpoint      248
Chelation therapy      54 408
Chemical exposure classes      11
Chemical mixtures      432
Chemical use classes      7
Chlordane      356 470
Chlordecone      473
Chlorfenvinphos      125
Chlorine      318
Chlorofluorocarbons      475
Chloroform      153 265 274 277
Chloroform metabolites      153 277
Chloromethylbenzene      144
Chlorpromazine      126 129 265
Chlorpyrifos      59 122
Chlorthiazide      265
Cholchicine      265
Cholestasis      266
Cholesterol      119
Cholinesterase      471 see
Chromatography      450—455
Chromatography, column      452
Chromatography, gas-liquid      404 451
Chromatography, high-performance liquid      404 454
Chromatography, paper      450
Chromatography, thin-layer      403 450
Chromium      46 53 318
Chromosome aberration tests      390
Chromosome translocation      245 248
Chronic toxicity      see Toxicity
Chronic value      473
Cigarette smoke, induction by      199
Cimetidine      129
Cirrhosis      266
Clara cells      318 323
Clean Air Act      412
Clean Water Act      412
Clearance      106
Clinical drugs      4 7
Clinical toxicology      see Toxicology
Clofibrate      139 191
Cloning, molecular      17
CNS      see Central nervous system
CoA      see Coenzyme A
Coal dust      318
Cobalt      4
Cocaine      205
Cocarcinogenesis      528
Coenzyme A (CoA)      146
Columns      450 451
Combustion products      7
Compartment      106 528
Compartmentalization      204
Comprehensive environmental response, compensation and liability act (CERCLA)      413
Conjugation reactions      see Phase II reactions
Constitutive active receptor (CAR)      195
Consumer products safety act      354 413
Consumer products safety commission improvements act      413
Contact hypersensitivity      337—338
Controlled substances act      413
Cooxidation      132
copper      4 165 166 492
Cortisol      300
Cosmetics      71
Coumaphos      126
Coumarin      122 138
Courtroom testimony      399 400
Covalent binding      274 384 527
COX-1      132
COX-2      132
Creatinine, plasma      274
Critical periods      255
1 2 3 4 5
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