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Авторизация |
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Поиск по указателям |
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Hodgson E. — A Textbook of Modern Toxicology |
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Предметный указатель |
Pregnancy, effects on metabolism 171
Pregnane X receptor (PXR) 196 197
Pregnenolone-16?-carbonitrile 191
Prevention of toxicity 411—421
Primitive streak 252
Procarcinogen see Carcinogen
Procedural manuals 24
Progesterone 119
Progression 241
Proguanil 122
Promazine 265
Promethazine 129
Promoter insertion 245
Promotion 241—243 537
Propanolol 138
Propiconazole 310
Propofol 122
Prospective assessment 479—480
Prostaglandin synthase 132
Prostaglandin synthaseand cooxidation 112
Prostaglandins 132 274
Protein binding 97 270
Protein effects on metabolism 163
Protein, stabilization 198
Protein, synthesis 17 264 266
Proto-oncogene 245
Pulmonary toxicity see Toxicity
Puromycin 265
Pyrethroid insecticides 61 222 477
Pyridoxine 165 166
Pyrrolizidine alkaloids 265
QA/QC manuals 24
QSAR see Quantitative structure activity relationships
Quality assurance 27
Quality control 27
Quantitation 26
Quantitative structure activity relationships (QSAR) 537
Quinidine 123 187
Quinones 151
Radiation 237
Radioimmunoassay 21
Rainbow trout 394
Rapamycin 123
RAS 246—247
RCRA see Resource conservation and recovery act
Reactive intermediates (metabolites) 149—161 269 538
Reactive oxygen 149 151 267 322
Receptors, androgen 309
Receptors, ecdysone 307
Receptors, ecological 505—506 508
Receptors, estrogen 303 306 308
Receptors, glucocorticoid 309
Receptors, hormone receptor agonists 306
Receptors, hormone receptor antagonists 308
Receptors, nuclear 302—303
Receptors, retinoic acid 307
Receptors, retinoid X (RXR) 195 196 304 308 315
Receptors, steroid 303
Receptors, thyroid 303
Red book 367
Reduction reactions 133—135
Reference Dose (RfD) see Acceptable daily intake
Regulation, of toxic chemicals 353—354 411
Regulatory agencies 354
Renal elimination 205—207
Renal system see also Kidney
Renal system, blood flow 274
Renal system, cortex 273
Renal system, function 273
Renal system, structure 273
Renal system, susceptibility 274—275
Renal system, tubules 273 274 275
Renin 274
Reproductive physiology, female 346—347
Reproductive physiology, male 343—344
Reproductive toxicants see Toxicants
Reproductive toxicity see Toxicity
Resistance see Adaptation to toxicants
Resource conservation and recovery act (RCRA) 414 538
Respiratory system and elimination 210
Respiratory system, anatomy 317
Respiratory system, cell types 317
Respiratory system, function 317
Respiratory system, lungs 210
Respiratory system, susceptibility 320
Respiratory toxicity see Toxicity
Retinoic acid 122 304
Retinoic acid receptor see Receptors
Retinol 122
Retrospective assessment 479—480
RfD see Acceptable daily intake
Riboflavin 165 166
Rifampicin 123 191 196
Risk analysis 538
Risk assessment 8 423—438 521 538
Risk assessment, environmental 501—517
Risk assessment, non-cancer 427—428
Risk characterization 426—427
Risk communication 8
Risk management 8 503 521
Risk toxicologic 538
RNA, hnRNA 17
RNA, mRNA 17
RNA, processing 17
RNA, translation 17
Rodenticides 63
Rotenone 223
Rubella virus 257
RXR see Receptors
S-Adenosyl methionine (SAM) 141
S9 113 385
Safe drinking water act 412
Safety factor 538
Safety pharmacology studies 364
Safrole 127 265
Salmonella assay 249
Sample preparation 447—448
Sampling, air 443
Sampling, soil 444
Sampling, tissue 445
Sampling, water 445
Sarin 200
Schwann cells 284 287—288
Segment II study 371 374—378
Selectivity (selective toxicity) 172 181 524 538
Selegiline 122
Senescence, effects on metabolism 167
Serotonin 142
Serum enzymes 274
Sexual behavior 345 348
Sexual characteristics, secondary 300
Sexual differentiation 300
Sexual function 300
SHBG 305 306
Signal transduction 242 246
Silica 318
Silicosis 321
Sinusoids 207
Sister chromatid exchange 390
SKF 525A 185 186
Skin 204
Slope factor 433
Soil pollutants 40
Solvents 70 539
Somite 253
Southern blot analysis 18
Spectrometry, bimolecular interaction analysis-mass 459
Spectrometry, induced coupled plasma 457
Spectrophotometry, infrared 459
Spectrophotometry, ultraviolet / visible 460
| Spectroscopy, atomic absorption 456
Spectroscopy, mass 458
Sperm quality 345
Spermatogenesis 344
Standard operating procedures 24
Starvation, effects on metabolism 165
Steroid receptor see Receptors
Stilbestrol 176
Streptomycin 276
Stress, effects on metabolism 200
Stressors, ecological 502
Stressors, response profile 510 512
Stressors, sources 507 513
Stressors, susceptibility 504
Structure-activity relationships 6 354 395
Styrene 7,8-oxide 137
Subchronic toxicity see Toxicity
Suicide inhibitor 155
Suicide substrate 151 189
Sulfanilamide 265
Sulfate 209
Sulfate conjugation 139
Sulfhydryl oxidation 270
Sulfotransferase (SULT) 139 140
Sulfoxide reduction 135
Sulfur dioxide 318
Sulfur oxides 36
Superoxide anion 322 525
Superoxide dismutase 525
Surface area 203
Susceptibility, ecosystem 504
Sweat 204
Sympathetic nervous system 280 291
Synapses 280 282 290
Synapses, postsynaptic 280 281
Synapses, presynaptic 280 282 290
Synergism and potentiation 189 381 539
Talc 318
Tamoxifen 123 129 308
Tannic acid 265
Taxol 122
TCDD 191 239 242 464 468 476
Temperature, effects on metabolism 200
Teratogenesis 6 251—259 343 539
Teratogenesis, multi-generation study 258
Teratogenesis, single-generation study 258
Teratology 251 374—378
Testes 170 300
Testing guidelines 257—258
Testosterone 169 300 305 310 311
Tetanus toxin 292
Tetrachloroethylene 265 318
Tetrachloromethane 153
Tetracycline 181 265
Tetrafluoroethylene 278
Tetrodotoxin 173
Thalidamide 256
Thelarche 313
Therapy 539
Thermal desorption 403—404
Thiobenzamide 129
Thiophenol 138
Thioridazine 265
Thiourea 182
Threshold 219 220
Threshold dose 10 539
Threshold limit value(s) (TLV) 44 418 539
Threshold limit value(s) (TLV), ceiling (TLV-C) 418 539
Threshold limit value(s) (TLV), short-term exposure limit (TLV-STEL) 418 539
Threshold limit value(s) (TLV), time-weighted average (TLV-TWA) 539 418
Thyroid 300 303 304 310 311
Thyroid hormones 169 300
Thyroid receptor see Receptors
Thyroxine 300 301
TK locus 387
TLV see Threshold Limit Value
TOCP see Tri-o-cresylphosphate
Tolbutamide 123
Tolerance see Adaptation to toxicants
Tolerance reassessment advisory committee (TRAC) 415
Toxic action, mechanism of 5
Toxic action, mode of 5
Toxic substances control act (TSCA) 414 540
Toxicant(s), chemical effects, on metabolism 184—199
Toxicant(s), comparative effects, on metabolism 172—183
Toxicant(s), definition 3 537 540
Toxicant(s), developmental effects, on metabolism 166
Toxicant(s), distribution 97—105
Toxicant(s), elimination 203—211
Toxicant(s), environmental effects, on metabolism 199—200
Toxicant(s), environmental movement 11
Toxicant(s), fate and effect 5
Toxicant(s), food chains 11
Toxicant(s), genetic effects, on metabolism 172—183
Toxicant(s), measurement of 6
Toxicant(s), metabolism 111—148
Toxicant(s), nutritional effects, on metabolism 163—166
Toxicant(s), physiological effects, on metabolism 166—172
Toxicant(s), reproductive 344—348
Toxicant(s), selective 524
Toxicity, acute 215—224 470 471 525
Toxicity, acute toxicity tests 359—363 525
Toxicity, assessment, definition 353
Toxicity, behavioral 343 527
Toxicity, behavioral toxicity testing 379—381 383
Toxicity, chronic 472 528
Toxicity, chronic toxicity tests 370—371 528
Toxicity, cytotoxicity 529
Toxicity, definition 3
Toxicity, developmental 343 371—378 380
Toxicity, genotoxicity 322 533
Toxicity, genotoxicity testing 385—393
Toxicity, hepatotoxicity 263—272 274 277 533
Toxicity, immunotoxicity 327—338 533
Toxicity, inhalation 357
Toxicity, measurement of 6
Toxicity, nephrotoxicity 273—278 536
Toxicity, neurotoxicity 174 279—297 536
Toxicity, neurotoxicity testing 378—381
Toxicity, prevention 411—421
Toxicity, pulmonary 537
Toxicity, reproductive 343—349
Toxicity, reproductive toxicity testing 371—378
Toxicity, respiratory 317—325
Toxicity, selective 538
Toxicity, subchronic 539
Toxicity, subchronic toxicity testing 363—370
Toxicity, testing 6 353—397 533
Toxicity, testing requirements, summary 355
Toxicity, testing, routes of administration 356
Toxicity, testing, selection of test species 366
Toxicokinetics 105—109 382 540
Toxicologic pathology 6
Toxicology work sheet, forensic 402
Toxicology, analytical 6 441—461
Toxicology, applied 6
Toxicology, behavioral 5 527
Toxicology, biochemical 4 524
Toxicology, clinical 6 399—409
Toxicology, comparative 528
Toxicology, definition and scope 3 540
Toxicology, developmental 251
Toxicology, ecotoxicology 464
Toxicology, environmental 7 530
Toxicology, forensic 7 399—409 532
Toxicology, history 8 399
Toxicology, industrial 7 533
Toxicology, molecular 5 524
Toxicology, nutritional 5
Toxicology, occupational 399
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