|
|
Àâòîðèçàöèÿ |
|
|
Ïîèñê ïî óêàçàòåëÿì |
|
|
|
|
|
|
|
|
|
|
Twyman R.M. — Advanced Molecular Biology: A Concise Reference |
|
|
Ïðåäìåòíûé óêàçàòåëü |
Silencers 377 454 452
Silent mutation 204
Simple sequence DNA 142
Simple sequence length polymorphisms 150 211
SINEs 96 142 144
Single stranded (DNA) binding protein 295 399
Single stranded DNA viruses 473—474
SIR proteins 377 454
Sister chromatid exchange 54 376
Site-directed mutagenesis 346—347f
Site-specific recombination 370 378—379 385—386
Site-specific recombination in transgenic organisms 353
Slow transforming retroviruses 258
SMAD family 431
Small nuclear RNA (snRNA) 224
Small nuclear RNA (snRNA), role in splicing 415—416
Somatic cell hybrids 152
Somatic hypermutation 219—220
Somatic mutation 201 253—258
Somatic recombination 379
Sonic hedgehog 91—92 138
SOS mutagenesis 197—198
SOS response 197
SOS response, induction of bacteriophage 198—199
Southern blot/hybridization 357—358
Southwestern screen 249—250 358
Specification autonomous 68f
Specification conditional 68f
Specification in development 71
Spheroplasts 361
Spliced leader RNA 420
Spliceosome 415—416
Splicing factors 416
Sporulation in Bacillus subtilis 78—79bx
Squelching 453
SR proteins 416
SRY 75
SSCP analysis 37
start 25 28—29
stats 429 442
Stem cell 72
Stem-loop 230—231
Steroid receptors 431
Stop codon 127
Strand slipping (see “Replication slipping”)
Stringency 357
Stringent control, stringent plasmids 272 277
Substitution fidelity 183—184
Subtractive hybridization 336
Subviral agents 467 477—481
Suicide enzyme 190
Supercoiling 232 233—234bx
Superfamilies 297
Suppression 10t 220—22lbx
SV40 472
Svedberg units 320
Switch regions 382
Synonymous mutation 204
Synteny 374
T-cell receptor genes 386—387
T-cell receptors 386—387
T-vector 283
Target site duplication 167f
Targeted mutation by homologous recombination 352
Targeted mutation, spontaneous 185
Targeting vectors 351—352 360
Tat-Tar 421 485
TATA box 448
TATA-binding protein (TBP) 242 447
Tautomeric shifts 184
Tautomers 184 223
TBP-assoriated factors (TAFs) 242 449
Telomerase 61—62f
Telomeres 61—62 405
Temperate phage 468
Terminal deoxynucelotidyl, transferase 324 408
Terminal redundancy 472
Termination codon 127
Tetrad analysis 160
TFIID 449
TFIIH 193 449
Thallasemias 216—217
Thermal melting profile of DNA 357
Threshold character 11
Ti plasmid 273 349 362—363
Ti vectors 362—363
Tn3 resolvase 386
Topoisomerase 397 398t
TP53 gene (see “p53”)
Trans-acting factors 113 452
Trans-sensing 7 114
Trans-splicing 266—268 420
Transcribed spacer sequences 106—107
Transcript analysis 338—339t
Transcription 443
Transcription factors, activation by signaling proteins 440—441 455—456
Transcription factors, activation domains 464—465bx
Transcription factors, combinatorial activity 456
Transcription factors, constitutive 448
Transcription factors, dimerization domains 244
Transcription factors, DNA-binding domains 237—243
Transcription factors, examples and binding sites 459t
Transcription factors, mechanism of action 451—455
Transcription factors, regulation of activity 455-456
Transcription unit 106
Transcription, initiation in bacteria 445—447
Transcription, initiation in eukaryotes 447—450
Transcription, principles 444—445
Transcription-coupled repair 192—194
Transcriptional arrest 458
Transcriptional elongation, regulation of 458—459
Transcriptional initiation, bacteria 445—447
Transcriptional initiation, RNA polymerase I 448
| Transcriptional initiation, RNA polymerase II 448—449
Transcriptional initiation, RNA polymerase III 450
Transcriptional map 155
Transcriptional regulation, -globin gene 462—463bx
Transcriptional regulation, bacteria 456—458
Transcriptional regulation, eukaryotes 458—459
Transcriptional regulation, lac operon 463—464bx
Transcriptional termination 460
Transduction 120—123
Transduction, generalized 120 122
Transduction, specialized 122—123
Transfection of bacteria 118
Transfection of eukaryoric cells 348 349t 361
Transfer RNA (tRNA) 224 314—315
Transfer RNA (tRNA), adaptor role in protein synthesis 314—315
Transfer RNA (tRNA), charging 127—129 315
Transfer RNA (tRNA), processing 411—412
Transfer RNA (tRNA), structure 314—315 321-322bx
Transfer RNA introns 418
Transformation of bacteria, natural 118 119—120
Transformation, artificial of E. coli 330
Transforming growth factor- superfamily 430—431
Transgenesis 348—353
Transgenesis, inducible transgene activity 353
Transgenesis, random integration of DNA 350—352
Transgenesis, site specific recombination systems 353
Transgenic animals and plants 348—349
Transition 202
Translation 127—129
Translation, regulation (see “Protein synthesis”)
Translesion synthesis 198 394—395
Translocation in protein synthesis 318
Translocation, chromosome mutation 51—53f
Translocation, reciprocal 52—53f
Transmissible spongiform encephalopathy 479—481
Transplacement 350—35lf
Transposable elements 165
Transposable elements, class I (see “Retroelements”)
Transposable elements, class II (see “Transposons”)
Transposable elements, classification 175—182
Transposable elements, uses 175 176t
Transposase 165
Transposition 165 370
Transposition, aberrant 174
Transposition, consequences of 172—175
Transposition, conservative and replicative 167—169
Transposition, mechanisms 166—170
Transposition, regulation 170—172
Transposon tagging 176 344
Transposons 175—180
Transvection 114
Transversion 202
Triple helix 231
Triple helix therapy 365—366
Triplet 127
Triplet repeat syndromes 218bx
Tumor suppressor genes 253 258—260t
Tumor viruses 469
Turner’s syndrome 48
Two hybrid system 305 345
Ubiquitin, in protein degradation 310
Unassigned reading frame 127
Unequal crossover 207
Unequal exchange 207 208f
Unequal sister chromatid exchange 207
Unique sequence DNA 133 136
Unstable mutant alleles 172
Untranslated region 106
UV-induced DNA lesions 185—190
UvrABC nuclease 185—190
V(D)J recombination 380
V-gene segments 387
Variation, phenotypic 1 2
Variegation 54
Vectorette PCR 284
Very short patch mismatch repair 196—198
Viral oncogenes 254 256t
Virion 467
Viroids 273 478
virus 467
Viruses as gene transfer vectors 349
Viruses, infection strategy 468—469
Viruses, regulation of gene expression 475—477
Viruses, replication strategy 469—475
Virusoid 479
VNTR sequences 142 150
Vulval specification, Caenorhabditis elegans 85—86bx
Wee mutants 26
Western blot 307
Whole genome duplication 299—300
Wild type 201
Winged helix 239
Wingless 87—89bx
Wnt signaling proteins, Drosophila Wingless 87—89bx
Wnt signaling proteins, in vertebrate limb development 91—92bx
Wobble hypothesis, wobble rules 129 227
X-chromosome inactivation 5 100—101
X-inactivation center 100
X-linked inheritance 4—5f 15—16bx
X-ray crystallography 307—308
Xeroderma pigmentosum 189
XIST gene 99—101
Y-linked inheritance 5 15—16bx
YAC transgenic mice 351—352
Yeast artificial chromosome (YAC) 153 327—329 361
Yeast cloning vectors 360-36lbx
Z-DNA 229 230f
Zinc binuclear cluster 241
Zinc finger, 239—240f
Zinc finger, DNA recognition code 248—249t
Zinc finger, multicysteine 240—241
Zoo blot 155 358
Zygotic genes, Drosophila 83—85
|
|
|
Ðåêëàìà |
|
|
|