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Àâòîðèçàöèÿ |
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Ïîèñê ïî óêàçàòåëÿì |
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Twyman R.M. — Advanced Molecular Biology: A Concise Reference |
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Ïðåäìåòíûé óêàçàòåëü |
In situ hybridization 152 339 359
In situ PCR 284
In vitro mutagenesis 346—348
In vitro mutagenesis, systematic 347
In vitro packaging 330
In vivo footprinting 250
Incompatibility groups 276 277—278bx
Incompatibility of plasmids 272 275—276
Indel 205
Induced fit 244
Induction in development 69—71f
Induction of gene expression 114 463—464bx
Induction of latent virus 468
Induction, bacteriophage 483
Induction, community effect 70
Induction, homeogenetic 69
Induction, instructive 69
Induction, lateral inhibition 69—70f
Induction, morphogens in 69
Induction, permissive 69
Informational suppression 220—221
Informosome 412-413
Inhibition domains (of transcriptional repressors) 465
Initiation codon 127 130
Initiation factors, protein synthesis 316—317
Initiator tRNA, role in protein synthesis 316—317
Inositol phospholipids 436—438
Inositol-1,4,5-trisphosphate 436—437
Integrase, bacteriophage 385 484
Integrase, retroviral 165
Integrons 179—180
Interaction trap 345
Interference 160—161
Internal ribosome entry site 319
Intrabodies 366
Intrinsic termination of transcription 460
Intron-encoded proteins 417—418
Introns 104 137
Introns, origins and evolution 303
Introns, phase 302—303
Introns, splicing 416—417
Inverse PCR 284
Inverse transposition 174
Inversions 50—51f
ion channels 426
Iron response element 320 423—424
IS elements 176—177
Isoaccepting tRNAs 129 314—315
Isoallele 6 209 211
Isochore model 58 143—144
Isochromosomes 51
Isoelectric focusing 307 ch25
Isotropic bending 230
Isotypes 379
Isotypic exclusion 381
Iterons 276
J-gene segments 387
Jak-STAT pathway 429
Jelly roll motif 292
Jun, c-jun gene 254—258 441
Junk DNA 137
K-homology domain 244
Karyogram 134
Karyotype, abnormal 46t
Karyotype, normal 134
Killer factors 273
Killer plasmids 273 274
Killer system 272
Kinetochore 60—61
Kinetoplast DNA 268
Kissing complex 277
Klenow fragment 394
Klinefelter’s syndrome 48
Knudson, two hit hypothesis 258—259
Kozak consensus 317
Lac operon 463—464bx
Lampbrush chromosomes 60
Lariat intermediate 415
Leading strand — lagging strand model 390
Leaky allele 210
Lesions of DNA 185—186
Lethal allele 8
Leucine zipper 241 246
Licensing factor 29—30
Ligase chain reaction 285
lines 96 142 144
Linkage 9 373
Linkage equilibrium/disequilibrium 374
Linkage mapping 375 147—151
Linkage mapping, limitations to accuracy 159—161bx
Linkers 326
Linking number paradox 37
Lipid second messengers 436
Lipofection 349
Locus control region 41 451 462—463
Lod scores 148
Long range restriction map 338
Loops in polypeptides 290
Loss of function 210
Loss of heterozygosity 259
Lysogeny 468
Lytic infection 468
M phase 23
M phase/maturation—promoting factor 25—26
Macromolecules, determining mass 320bx
Macromolecules, separation 320 355
Macromutation 202
MADS box 73
Maintenance methylase 93
Major groove 228
MAP kinase 432—433t
Mapping function 160
MAT locus 377
Maternal effect 5—6 67f
Maternal genes, Drosophila 82—85bx
Maternal inheritance 263 264f
Mating type switching 377
Matrix-associated region 41
Mediator 453
Megaplasmids 271
Meiosis 373
Meiotic drive 6—8
Meiotic map 146
Mendelian inheritance 1—11
Mendel’s First Law 3
Mendel’s Second Law 8—9
Meristic character 11
Merozygote 117
Meselson — Stahl experiment 389—390
Mesoderm induction, Xenopus laevis 81
Messenger RNA (mRNA) 224 313
Messenger RNA (mRNA), life cycle in bacteria and eukaryotes 313—314
Messenger RNA (mRNA), processing 412—421
Metabolic block 215
Methylation interference assay 250t 251f
Microballistics 349
Microsatellite DNA 143
Minisatellite DNA 142—143
Minor groove 228
Misinstructional lesion 185
Mismatch 194
Mismatch repair, long patch 194—195
Mismatch repair, short patch 196—198
Missense mutation 204
Mitochondrial DNA, mutants 264—265t
Mitochondrial DNA, organization and gene expression 266—267
Mitochondrial DNA, replication 267—268
Mitochondriopathies 264
Mitosis 32
Mitosis, control of 30—32
| Mitosis, mitotic recombination 375
Mitosis, mitotic segregation 376
Mixoploidy 54
Mobile generic elements 165—182
Mobilization of plasmids for transfer 118
Model organisms, genomics 133 145—146t
Modules, of proteins 287 300—301
Molecular chaperones 39 294—295
Molecular clock 213
Molecular cloning 323
Molecular cloning, analysis of cloned DNA 336—339
Molecular cloning, general principles 323—331
Molecular cloning, recovery of cloned DNA 331
Molecular cloning, strategies 331—336 332t
Molecular markers 149—501
Monoallelic expression 5 97—100 381
Monocistronc mRNA 104
Monohybrid cross 3—4f
Monoploid number 134
Morbid map 50
Morphogenesis 65 73—75
Mosaic 54
Motif, in DNA or polypeptide sequence 301
Motif, in protein structure 290—211
mRNA guanyltransferase 408 413
Muller classification 209
Multienzyme proteins, evolution by gene fusion 302
Multigene families 136 139 298
Multiple cloning site 327
Multiple crossovers 160
Multiple start sites 448
Multiplex PCR 281
Mutagen 187 188t
Mutagenesis, gene targeting 349—353
Mutagenesis, in vitro 346—348
Mutagenesis, induced 183—188
Mutagenesis, natural mechanisms 183—188 207—208 172—175
Mutant 201
Mutant alleles 209—211
Mutation 183 201
Mutation frequency 212
Mutation hotspots 211
Mutation pressure 212
Mutation rate 183 212
Mutation screening 337t
Mutation, functional consequences 203—207
Mutation, structural categories 201—203t
Mutator/antimutator genes 183 393
Myc, c-myc gene 254—258
MyoD gene family 140
N-formylmethionine 130 305—306
N-glycosidic bond 224
N-region diversity 380
Natural selection 212—213
Neomorph 210
Nested genes 106
Nested PCR 280
Neutral mutation 203
Neutron scattering 308
Niewkoop center 80—82
NOESY 308
Nonallelic interactions 9—11ft
Noncoding region 106
Nonconjunction 49
Nonconservative mutation 204
Nondisjunction 49f
Nonhistone proteins 37 239
Noninstructional lesion 185
Nonreciprocal recombination 376—378
Nonsense codon 127
Nonsense mutation 204
Nonsynonymous mutation 204
Norm of reaction 13
Northern blot/hybridization 338 357—358
Northwestern screen 250 358
Nuclear localization sequences 310
Nuclear magnetic resonance spectroscopy 307—308
Nuclear matrix 38
Nuclear receptor family 241 431
Nuclear scaffold 38
Nucleases in molecular cloning 324t
Nucleases, biological roles 399
Nucleases, nuclease mapping 338—339t 340f
Nucleic acid hybridization 323 356—359bx
Nucleic acid hybridization in solution 357
Nucleic acid hybridization, parameters 356—357
Nucleic acid probes 359—360bx
Nucleic acid probes and nonisotopic labeling 360
Nucleic acid synthesis 407—408bx
Nucleic acid-binding proteins 235—252
Nucleic acid-binding proteins, recognition elements in 235—237
Nucleic acid-protein interaction (see “Protein-nucleic acid interaction”)
Nucleic acids 223
Nucleic acids, backbone 225
Nucleic acids, conformational polymorphism 223 230
Nucleic acids, helical morphology 228—230 233bx
Nucleic acids, primary structure 223—226 228f
Nucleic acids, secondary structure 226—231
Nucleic acids, tertiary structure 231—232
Nucleoid, structure and organization 42—43
Nucleolar organizer region 58
Nucleosides 224
Nucleosome 35—36f
Nucleosome structure during replication/ transcription 39
Nucleosome, core particle 35
Nucleosome, displacement 39
Nucleosome, phasing 37—339
Nucleotide excision repair 192—194
nucleotides 225 226f 227t
Null allele 210
Ochre codon 127 204
Ochre suppressor 220
Okazaki fragments 391
Oligonucleotide mutagensis 356—357f
Oligonucleotides 225
Oncogene activation mechanisms 255—258tf
Oncogenes 253—258 259 261
One gene one enzyme model 103
Opal codon 127 204
Opal suppressor 220
Open reading frame 106 127 313
Operator 452 463
Operon 107 456
Organelle genetics 263—265
Organelle genomes 263—269
Organelle plasmids 268
Organizer 80—82
Origin of replication 401—404
Orthologous genes 298
Overlapping genes 106
P-DNA 174
P-element 178—179
P-element mutagensis 344
P-site (peptidyl-tRNA site), of ribosome 314
P1 artificial chromosome (PAC) 153 329
p53 33 260 441 456
Packaging ratio 35
Packaging site 122
Padlock probes 360
Pair rule genes 83 84
Paired family 239
Paralogous chromosome segments 300
Paralogous genes 298
Paramutation 7 96
Paranemic joint 231
Parasexual exchange, bacteria 117
Parental imprinting 5 97—100f
Parental imprinting enhancer competition 98
Parental imprinting role in mammalian development 99—100
Partial redundancy 140
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