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Kambhampati D. (ed.) — Protein Microarray Technology
Kambhampati D. (ed.) — Protein Microarray Technology

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Название: Protein Microarray Technology

Автор: Kambhampati D. (ed.)

Аннотация:

This book is the first of its kind in the field of protein microarrays and addresses novel strategies for constructing highly functional and biocompatible microarrays for screening proteins.
The list of authors consisting of world leading experts provide a roadmap for solving the complex challenges that are currently faced while monitoring protein-protein interactions over a wide range of microarray platforms. In doing so, they also offer a comprehensive overview of microarray surface chemistry, detection technologies, fabrication options for array development, and data analysis of numerous types of protein interactions.


Язык: en

Рубрика: Computer science/Биоинформатика/

Статус предметного указателя: Готов указатель с номерами страниц

ed2k: ed2k stats

Год издания: 2004

Количество страниц: 268

Добавлена в каталог: 18.11.2005

Операции: Положить на полку | Скопировать ссылку для форума | Скопировать ID
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Предметный указатель
Acetylcholinesterase      21
Aldehyde      29
Aldehyde-siliane      13
Alkanethiol      17ff 34 107 111 113 119 124 128
Alkylsilane      12ff
Aluminium oxide      14
Aminated nylon      22f
Aminopropylsilane      13 15 28
Amperometric      21
Anthrachinone      29
Antibody      111 119 121 123ff 127
Antibody array      168 183
Antibody, anti-FLAG      123ff
Antibody, protein      123ff
Antibody-antigen interaction      23
Antigen reverse array      168
Arrays      107ff 111
Arrays, DNA      107ff
Arrays, peptide      107ff
Arrays, protein      107ff
Artificial nose      206
Atomic force microscopy      21 196ff
Auto-fluorescence      223
Automated flagging      225 235
Avi-tag      32f
Azidophenyl      29
Background contamination      225
Background estimation      232
Background intensity      223
Background pixels      219
Bar-coding      171
Batch automation      227
Bead      34
Biacore applications      77ff
Biacore applications, Alzheimer's disease      85
Biacore applications, amyloid b-peptide (Ab)      85
Biacore applications, angiogenesis      81
Biacore applications, apoptosis      77ff
Biacore applications, autoimmunity      84
Biacore applications, base pair mismatches      93ff
Biacore applications, binding site microenvironment      88
Biacore applications, cancer research      77ff
Biacore applications, cell cycle control      82
Biacore applications, clinical research      83ff
Biacore applications, clinical trials      80ff
Biacore applications, disease mechanism      86
Biacore applications, DNA analogs      94ff
Biacore applications, Drug interactions      92
Biacore applications, glutamate receptor      90
Biacore applications, growth factor receptors      77ff
Biacore applications, humanized antibodies      87
Biacore applications, immunogenicity      87
Biacore applications, immunoprecipitation      91
Biacore applications, inflammation      84ff
Biacore applications, inhibition, cytotoxicity      89ff
Biacore applications, lectin      84
Biacore applications, liposome      81
Biacore applications, membrane proteins      80ff
Biacore applications, monoclonal antibodies      79
Biacore applications, neuroscience      85ff
Biacore applications, nucleic acid structure      94
Biacore applications, peptide mimetics      77
Biacore applications, plasma membrane      80
Biacore applications, protein aggregation      86
Biacore applications, protein polymerization      85ff
Biacore applications, Purkinie cells      90
Biacore applications, receptor antagonists      77
Biacore applications, receptor/ligand interaction      79ff
Biacore applications, RNA      95ff
Biacore applications, screening      80
Biacore applications, signal transduction      80ff
Biacore applications, single nucleotide polymorphisms      93
Biacore applications, spinal muscular atrophy      91
Biacore applications, SPR-MS      84
Biacore applications, therapeutic reagents      77ff
Biacore assay formats      70
Biacore assay formats, direct binding assays      70
Biacore assay formats, inhibition assays      70
Biacore assay formats, sandwich assays      70
Biacore assay formats, surface competition assays      70
Biacore technology      59ff 62 63 68 70 71 74
Biacore technology, carboxymethylated dextran      62ff
Biacore technology, cornerstones      59ff
Biacore technology, hydrogel      62 74
Biacore technology, immobilization chemistry      63ff
Biacore technology, report points      68ff
Biacore technology, resonance unit (RU)      68
Biacore technology, sensorgram      68ff
Biacore technology, solution analysis      74
Biacore technology, surface preparation      71
Biacore technology, surface versus      74
Biacore technology, terminology      60
Binding      144
Binding concentration      229
Binding, non-specific      144
Binding, specific      144
Biochips      153 161ff
Biochips, affinity capture      161
Biochips, imac      161
Biochips, Immunoprecipitation      161
Biochips, Kinases      161
Biochips, mass spectrometry      153 161
Biochips, microarrays      162
Biochips, Phosphorylation      161
Biochips, SELDI      162
Biocompatibility      18
Bioelectronics      14
Biomolecular interaction      12 15
Biomolecular screening      33
Biomolecule Library      12
Biosensor      21 177
Biosensor technology      184
Biotin      19f 32f 184
Biotin-avidin      175
Biotinylated thiol      20
BSA      15 180
Calibration curves      148
cantilever      196ff
Cantilever array      197ff
Cantilever functionalization      204ff
Cantilever functionalization, antibodies      205
Cantilever functionalization, BSA      204
Cantilever functionalization, oligonucleotides      207
Cantilever functionalization, polyethylene glycol (PEG)      204
Cantilever functionalization, silanes chemistry      204
Cantilever functionalization, thiol chemistry      204
Cantilever, beam deflection      199
Cantilever, bimetallic mode      196
Cantilever, calibration      201
Cantilever, design and properties      198
Cantilever, interferometry      200
Cantilever, noise      200ff
Cantilever, pH detection      203
Cantilever, piezoresistive      200
Cantilever, resonance frequency      196 198
Cantilever, silicon      198
Cantilever, silicon nitride      198
Cantilever, spring constant      198 201
Cantilever, surface stress      197 202ff
Capacitance      27
Capture array      168
CCD camera      181
Cellulose      23
Central limit theorem      225
Chelate complex      33
Chip      26
Chip, structuring      26
Chromatography      156ff
Chromatography, affinity      157
Chromatography, anionic      157
Chromatography, biochips      156ff
Chromatography, cationic      157
Chromatography, charge      156
Chromatography, covalent      156
Chromatography, hydrophobie      156ff
Chromatography, IMAC      156
Chromatography, mass spectrometry      157
Chromatography, SELDI      157
Clustering      220
CMOS      27
Complementarity-determining region (CDR)      12
Complex coordination      27
Concentration level      231
Conducting polymer      21 27
Confidence value      225
Constants      132
Constants, affinity      132
Constants, kinetic rate      132
Contact printing      169ff 180
Contamination      219
Cooling      171
Copolymerization      24
Correlation ratio      222
Covalent binding      27
Creatine kinase      2098
Cross-linking      148
Cross-reactivity      99
CV      225
Cy-dye      179 182
Cy3      167 170 174 176 180f
Cy5      167 176 181
Cytokine      16 25 167 183f
Data quantification      222
Data tracking      171
Denaturation      15 176 179 180
Dendrimer      24
Deoxyuridine      31
Deoxyuridine, brominated      31
Derivatization      14
Derivatization, glass surface      14
Detection      181ff
Detection limit      25
Detection method      195
Detergent      171
Dextran      23
Dextran-hydrogel      22
Differential measurement      197ff
Differential measurement, noise      200ff
Direct Measurement      183
Discovery proteomics      99
Dissociation constant      175 187
DNA Arrays      165
EDC (N-3-dimethylaminopropyl-N-ethylcarbondiimide)      29
EDTA      33
Electrochemical detection      27
Electrode      21
ELISA      15f 27 183 185
Enzyme electrode      21
Epitope      32 124 127
Epitope, anti-FLAG      121
Epoxy groups      29
Epoxy-silane      13
Evanescent wave      60
evaporation      175 179 186
Expected position      226
Expression difference mapping      158
Expression difference mapping, biochips      158
Expression strength      222
Fab-domain      34
FAST      179
Fc-domain      34
Fluorescence detection      26
Fluorescence intensity      15
Fluorescence quenching      132
Fluorescence signal      15
Fluorescence spectroscopy      132
Fmoc      113ff
Foerster      134
Functional array      168 175 181 186
Functional array, protein-protein      181
Fusion protein      121 123 126 129
Gaussian distribution      234
Gaussian properties      234
Genomics      155
Genomics, yeast-2-hybrid      155
Genotyping      26
Germanium oxide      14
GFP      182
Glass slide      12ff 15f 24
Glass slide, aldehyde-coated      15
Glass slide, nickel complex-coated      16
Glass slide, silane-coated      24
Glucose      209
Glycerol      179f 186
Glycerol, functional arrays      179
Gold coating      199
Gold coating, coast cantilever      199
Gold substrate      17ff
GST yeast proteins      16
Gum acacia      180
High refractive index material      26
High-refractive      24
High-throughput      227
His-Tag      16 32f
Humidification      171
Humidity      179 181 186
Hybridization chamber      181
Hydrazide      34
Hydrogel      22f
Hydrogen peroxide detection      21
Hydrophilic surface      179
Hydrophobic      181
Hydrophobic surface      179
IgG      34 170 174 180 186
Ignored pixels      219
Image alignment      217
Image segmentation      219
Immobilization      32 40
Immobilization chemistry      64ff 67
Immobilization chemistry, adsorbed lipid monolayers      67
Immobilization chemistry, aldehyde coupling      65
Immobilization chemistry, amine coupling      64
Immobilization chemistry, capturing      66
Immobilization chemistry, Ligand thiol      65
Immobilization chemistry, Lipid bilayers      67
Immobilization chemistry, NTA      66
Immobilization chemistry, streptavidin-biotin      66
Immobilization chemistry, surface thiol      65
Immobilization chemistry, thiol coupling      65
Immobilization, biological affinitiy-based binding      40
Immobilization, chemical affinity system      40ff
Immobilization, covalent coupling      40
Immobilization, passive adsorption      40
Immobilization, phenyldiboronic acid (PDBA)      40ff
Immunoassay      34
Impedance Spectroscopy      27
In situ real-time monitoring      132
Index material      24
Integrated microarray      27
Intensity ratio      222
Intensity-based signal      219
Interaction      27 131 165 174 180f
Interaction discovery mapping      158
Interaction discovery mapping, biochips      158
Interaction, covalent      174 180
Interaction, electrostatic      174
Interaction, non-specifically      180f
Interaction, Poly L-Lysine      174
Interaction, protein-protein      165 181
Interaction, proteomics      99
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