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| Авторизация |
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| Поиск по указателям |
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| Kambhampati D. (ed.) — Protein Microarray Technology |
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| Предметный указатель |
Interaction, salt bridge 174
Interaction, solid-water interface 131
Isothiocyanate 29
Kolmogorov — Smirnov tests 234
Kretschmann 136
Lab-on-a-chip 25 26
Label-free detection 195 207
Label-free detection, DNA oligonucleotides 207f
Label-free detection, hybridization 207f
Label-free detection, proteins 208f
Label-free detection, single-base mismatch 207
Laboratory Information Management System 171
Laser scanner 181
Lipoic acid 144
Log-normal 223
Luminescence assay 27
Maleimide 13 29
Mannitol 18
Manual flagging 235
Mass spectrometry 18 22 27 97 183
Mass spectrometry, ESI 97
Mass spectrometry, MALDI-TOF 97
Mass transport 76
Mass transport in concentration assays 76
Mass transport in kinetics assays 76
Mass transport, diffusion coefficient 76
Mass transport, re-binding 76
Matched filtering 218
Matrix 132ff
Matrix, Dextran 133
Mean 222
Median 222
Methacrylate 24
MICA 14
Micro-capillary electrophoresis 27
Microarray plate 179
Microarray smearing 15
Microchannel 26f
Microcontact printing 16 21
Microelectrode structure 27
Microfluidic channels 110 113 127
Microfluidic device 25ff
Microfluidics 25
Microfluidics system 67 75
Microfluidics system, flow cell 67ff
Microfluidics system, hydrodynamic addressing 67
Microfluidics system, IFC 75
Microfluidics system, integrated microfluidic cartridge 67ff
Microfluidics system, laminar flow 75
Mixed monolayer 18 21
MODE 222
Monolayer 27
MutS proteins 116ff
Myoglobin 2098
N-hydroxy-succinimide ester 29
Nanomechanical cantilever sensor 195ff
Neurotoxins screening 21
Ni-NTA complex 13 33
Nitrocellulose 22f 25 27
Non-contact printing 169
Non-specific adsorption 15
Non-specific interaction 23
NTA capture agents 124ff
Nylon 23 27 29
Nylon membrane 25
Oligo ethylene glycol 18
Oligonucleotides 207
Open perimeter 227
Orientation 16
Oriented surfaces 175
Outliers 221
p-value 225
p53 167 175
Particle lithography 21
PDMS 110 113 119ff 126
PDMS, peptides 119ff
peg 119 121
PEG, anti-Myc 119
Percentage, ignored pixels 226
Percentage, open perimeter 227
pH detection 203
pH detection, cantilever 203
Phenyldiboronic acid 31
Photoaptamer 31
Photochemical cross-coupling 29
Photografting 24
Photoimmobilization 21
Photopatterning 107ff 113ff 126
Photopatterning, protein 120ff
Photoreaction 16
Photoreaction, aldehyde coated 16
Photoreaction, glass slide 16
Photoreactive group 29
Piezo 169
Plasmons 60
PMMA 29
Polyacrylamide 22 23
Polyethylene 29
Polyethylene glycol (PEG) 113
Polylysine 12 15 28
Polymer brush 22f
Polymer gel 24
Polymer membrane 22f
Polymethyl methacrylate 27
Polypropylene 29
polystyrene 22 29
Polyvinylpyrrolidone 180
Position offset 226
Post-translational modification 99 165 183 188
ppH 203
Preparation 24
Printing buffer 179 186
Prostate specific antigen 209
Protein A 34
Protein A-IgG 208
Protein arrays 99 169
Protein arrays, data complexity 99
Protein arrays, size of 99
Protein arrays, technical challenges for 99
Protein labeling 182
Protein labeling, chemical 182
Protein labeling, fluorescent fusion proteins 182
Protein labeling, radiolabeling 182
Protein microarray 39 168
Protein microarray systems 98ff
Protein microarray, application 39
Protein microarray, platform optimization 39
Protein microarray, types of 168
Proteomics 58ff 98ff 154ff 159ff
Proteomics, affinity precipitation 155
Proteomics, Amyloid b 159
Proteomics, biochips 159ff
Proteomics, challenges for in relation to genomics 98
Proteomics, elektrospray 154
Proteomics, ELISA 155
Proteomics, interaction discovery mapping 159
Proteomics, MALDI 154
Proteomics, mass spectrometry 154 156 159
Proteomics, protein biochips 156
Proteomics, protein interactions 159
Proteomics, protein microarrays 156
Proteomics, SELDI 154 156
Proteomics, troponins 160
Proteomics, Western Blot 155
Pyridyl disulfide 29
Quality control 223
Quality flagging 235
Quality measurements 223
Quality measures 223
Quality values 223
| Quantification method 230
Quartz 14
Radioimaging 22
Ratio estimation 233
Redox-active label 27
Reflectance of light 24
Reflective slide 25
Reflectivity signal 136
Refractive index 24
Regeneration 66 68 72ff 145f
Regeneration, number of cycles possible 72
Regeneration, optimal solution 72
Region-growing 222
Replicate measurements 229
Replicate standard deviation 229
Reproducibility 25
Resonance 61
Resonance, refractive index contribution 61
Response regulators 116ff 128
RNA 107 121ff 125 127
RNA, DNA 125ff
Rolling circle amplification 184
Salicylhydroxamic acid (SHA) 32 40ff
Sample dilution 180
Sample volume 179
Sandwich assay 25 183
Sandwich detection 139ff 142
SATP 111ff 119
Scanning tunneling microscopy 21
Segmentation 219 220ff
Segmentation, circular 219
Segmentation, hybrid 222
Segmentation, Mann-Whitney 220
Segmentation, method 229
Segmentation, spatial 219
Segmentation, trimmed measurements 221
SELDI 153
Self-assembled monolayer 13 17f 23f 177
Semiconductor chip 14 25ff
Semiconductor surface 27
Serial dilution 179
Shape regularity 227
Signal contamination 225
Signal estimation 229
Signal intensity 25 223
Signal volatility 225
Signal, to-noise ratio 20 31
Silanization 13
Silicon 14
Silicon oxide 14
Silicon wafer 119
Site-specific immobilization 34ff
Slide, 2-D SHA coated 41 42 48
Slide, 2-D SHA coated, intrisic fluorescence 48ff
Slide, 2-D SHA coated, non-specific protein binding 48ff
Slide, 2-D SHA coated, preparation 42
Slide, 3-D SHA coated 41 48 51
Slide, 3-D SHA coated, intrisic fluorescence 48ff
Slide, 3-D SHA coated, non-specific protein binding 48ff
Slide, 3-D SHA coated, PDBA-Protein conjugate 51ff
slides 167 169 172ff 174ff 180ff 186
Slides, acrylamide 173 175 180
Slides, agarose 177
Slides, aldehyde 167 172ff 180
Slides, amine 172ff
Slides, BSA-NHS 174
Slides, derivatized glass 167 169 172 186
Slides, epoxy 172ff
Slides, FAST 173 177 180
Slides, GAPS 173
Slides, HydroGel 176
Slides, HydroGel-coated 173
Slides, nickel 167 173 175 181
Slides, nitrocellulose 173 177 180 186
Slides, poly L-lysine 167
Slides, storage 51
Slides, streptavidin 173 180
Software 171
Solid pins 170 174 180
Solute array 168
Spacer molecule 20
SPFS 135 145
SPFS, concentration 145
SPFS, Instrumentation 135
Split pins 170f 179
Spot 171 177 179ff 185 218f
Spot contamination 219
Spot density 171
Spot finding 217
Spot intensity 177 179 185
Spot location 218
Spot morphology 179ff
Spot shape 218
Spot size 177 218
Spot tracking 171
Spot, amount of sample 179
Spot, surface-to-volume ratios 179
SPR 23 57ff 115ff 120ff
SPR imaging 113ff
SPR-MS 59 97ff
SPR-MS, combination of technologies 97
SPR-MS, MALDI target 98
SPR-MS, methods of combining SPR and MS 98
SSMCC 111ff 119
Stability 186
Standard operating procedures 177ff
Storage 25
Strep-Tactin 33
Strep-Tag 32f
Streptavidin 13 19f 32f 175
Streptavidin surface 19ff
Styrene 24
Supramolecular 27
Surface chemistry 171
Surface concentration 137
Surface concentration, SPR signal conversion 138
Surface matrix 132
Surface modification 23
Surface patterning 21
Surface plasmon field-enhanced fluorescence spectroscopy (SPFS) 131—133 135 137 144
Surface plasmon field-enhanced fluorescence spectroscopy (SPFS), fluorescence profile at the interface 133
Surface plasmon field-enhanced fluorescence spectroscopy (SPFS), instrumentation 135
Surface plasmon field-enhanced fluorescence spectroscopy (SPFS), LOD evaluation 144
Surface plasmon field-enhanced fluorescence spectroscopy (SPFS), SPR signal conversion 137ff
Surface plasmon resonance (SPR) 18 57ff 60 69 70 72ff
Surface plasmon resonance (SPR), absolute response 69
Surface plasmon resonance (SPR), bulk effects 74
Surface plasmon resonance (SPR), bulk response 69
Surface plasmon resonance (SPR), detection limit 70
Surface plasmon resonance (SPR), detection princips 60ff
Surface plasmon resonance (SPR), drug compounds 74
Surface plasmon resonance (SPR), excluded volume effect 74
Surface plasmon resonance (SPR), experimental design 73
Surface plasmon resonance (SPR), imaging 107ff 108ff
Surface plasmon resonance (SPR), immobilization levels 72
Surface plasmon resonance (SPR), non-specific binding 73
Surface plasmon resonance (SPR), relationship of SPR 69 72
Surface plasmon resonance (SPR), relative response 69
Surface plasmon resonance (SPR), response to binding 69
Surface plasmon resonance (SPR), response to molecular weight 72
Surface plasmon resonance (SPR), Rmax 72
Surface plasmon resonance (SPR), solvent correction 74
Surface plasmon resonance (SPR), specific refractive index increment 70
Surface plasmon resonance (SPR), specificity 73
Surface plasmon resonance (SPR), SPR angle 60ff
Surface property 18
Surface stress 202ff 207
Surface stress origin 202ff
Surface stress, DNA oligonucleotides 207
Surface stress, hybridization 207
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