Van Eyk J.E., Dunn M.J. — Proteomic and genomic analysis of cardiovascular disease :: Электронная библиотека попечительского совета мехмата МГУ

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Van Eyk J.E., Dunn M.J. — Proteomic and genomic analysis of cardiovascular disease

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Название: Proteomic and genomic analysis of cardiovascular disease

Авторы: Van Eyk J.E., Dunn M.J.

Аннотация:

This is a delightful book with something to offer both novice and experts in the field.

Язык:

Рубрика: Медицина и здравоохранение/

Статус предметного указателя: Готов указатель с номерами страниц

ed2k: ed2k stats

Год издания: 2003

Количество страниц: 396

Добавлена в каталог: 11.12.2005

Операции: Положить на полку | Скопировать ссылку для форума | Скопировать ID

Предметный указатель

$Ca^{2+}$ /CaM-dependent protein kinase (CaMK)      268
(MS/MS/MS)      197
$[^{35}S]$ methionine      308
$\beta$ -adrenergic kinase 1 (bARK1)      349
$\beta$ -adrenergic stimulation      55
$\beta$ -blocker      344
$^{32}P-\gamma$ -ATP      280
2D-DIGE      see two-dimensional differential gel electrophoresis
2D-PAGE      see two-dimensional polyacrylamide gel electrophoresis
2DE      see two-dimensional polyacrylamide gel electrophoresis
2DE protein databases      187
Acetaminophen      375
Acetylation      173
Adenovirus      38
Adhesion molecule      142
Affinity chromatography      206 208 295
Affinity chromatography, antibody      207
Affinity chromatography, ATP sepharose      263
Affinity chromatography, immunoprecipitation      297
Affinity chromatography, molecular tag      207
Affinity chromatography, recombinant protein-based affinity pull down      297
Affinity chromatography, tagging      368
Affinity chromatography, tandem affinity purification (TAP)      368
Affinity purification      189
Algorithms, hierarchical clustering algorithms      17
Algorithms, k-means clustering      18
Algorithms, self-organizing maps      18
Algorithms, supervised learning      16
Algorithms, un-supervised learning      17
Aneurysms      168
Angiotensin      53
Angiotensin II      307
Angiotensin II receptor 1 blocker      345
Angiotensin-1 converting enzyme      1 (ACE-1)
Angiotensin-1 converting enzyme, inhibitor      344
Animal model      351 361
Animal model, alcohol      188
Animal model, atherogenesis      141
Animal model, balloon injury      166
Animal model, dilated cardiomyopathy (DCM)      187
Animal model, enteroviral model      53
Animal model, familial hypertrophic cardiomyopathy (FHC)      27
Animal model, heart failure      188
Animal model, ischemia      92
Animal model, ischemia/reperfusion      89 322
Animal model, isoproterenol      36
Animal model, male/female differences      105
Animal model, myocardial ischemia      88
Animal model, neonatal cardiomyocytes      38
Animal model, pacing-induced      188
Animal model, pressure-overload      10
Animal model, toxicity      188
Animal model, transgenic animal      28 347
Antibody array      238
Antibody array, synthetic phage-displayed antibody      240
Antisense oligonucleotides      347
Aorta      137 160
Aortic smooth muscle cell      114
Apolipoprotein E (ApoE)      377
Apoptosis      48 311
Aptamer, nucleic acid      240
Aptamer, random peptide      240
Arrhythmia      46
Artifactual modifications      174
Atherogenesis      139
Atherosclerosis      141 377
ATP binding cassette 1 (ABCA1) protein      347
ATP-binding cassette proteome      272
Autopsis      141
Bead-bases sequencing      127 129
Binding domain      301
Binding partners      see protein complexes
Bioinformatics      35 185 341
Bioinformatics, resources      204
Bioinformatics, web      186
Biological network      227
Biomarker      293 333 364 377
Biosensor      244
Biotech drugs      342
Calcineurin      102
Calcium homeostasis      186
Calcium signaling      55
Cancer      74 216 372 377 378
Candidate gene approach      28
Capillary isoelectric focusing (CIEF)      367
Cardiac muscle      317
Cardiac remodeling      47
Cardiac-specific antigens      189
Cardiochip      54
Cardiomyopathy      370
Cardioprotective genes      99
Cardiorespiratory      317
Cardiovascular disease      23 369 377
CDNA microarray      3
CDNA microarray, protocols      5
Cell cycle      76
Cell fractionation      206 324
Cell signalling      55
Cellular network      293
Chemical libraries      363
Cholesterol      374
Cholesteryl ester transfer protein (CETP)      347
Chromophore-assisted laser inactivation (CALI)      369
Chronic obstructive pulmonary disease (COPD)      317
Clinical evaluation      364
Clinical validation      75
Cluster      162
Clustering      132
Co-translational modification      173
Collagen      165
Combinatorial libraries      349
Compensatory change      105
Contractile protein      27 319
Coomassie blue      330
Coomassie silver      298
Coronary artery disease      46
cot      88
Cross hybridization      135
CyPA      311
Cytochrome P450      160
Cytosol      287
Data analysis, algorithms      68
Data analysis, average difference      11
Data analysis, background      11
Data analysis, clustering      132
Data analysis, clustering algorithms      14
Data analysis, confidence interval      107
Data analysis, expression ratio      14
Data analysis, flawed array      12
Data analysis, hierarchical clustering      15 69
Data analysis, k-means clustering      16 70
Data analysis, multidimensional scaling (MDS)      72
Data analysis, normalization      13 70
Data analysis, principal components analysis (PCA)      72
Data analysis, reproducibility      15
Data analysis, scaled data      71
Data analysis, self-organizing map (SOM)      72
Data analysis, signal intensity      143
Data analysis, software      11
Data analysis, statistical methods      71
Data analysis, supervised learning      14
Data analysis, unsupervised learning      15
Data analysis, Venn diagram      134
Data analysis, “front-end” analysis      34 36
Database searching      86 185
de novo sequencing      204
Detergent      174
devices      244
Diagnostic marker      75 156
Diaphragm      317 322

Differential display      85
Differential gel electrophoresis (DIGE)      181
Differential protein profile      229
DIGE      see differential gel electrophoresis
Disease pathways      359
DNA microarray chip      341
DNA-protein interaction      302
Dot blots      117
Drug design      361
Drug discovery      341 360
Drug screening      271
Drug targets      344 360 364
Early response genes      131
Electroendosmotic flow      175
Electrospray ionization (ESI)      183 259
Endothelial cell      142 160
Endothelial nitric oxide synthase (eNOS)      100 161
eNOS      see endothelial nitric oxide synthase
ERK1/2      see extracellular signal-regulated kinases
ESI      see electrospray ionization
ESI-TOF MS      366
Expression profiling      341 346
Expression sequence tag (EST)      29
Expression sequence tag (EST), gene mutations      50
Expression sequence tag (EST), human genome project      50
Extracellular matrix      54
Extracellular signal-regulated kinases (ERK1/2)      307 371
Fabry disease      344
Familial hypercholesterolemia      344
Familial hypertrophic cardiomyopathy (FHC)      321
Federal drug administration (FDA)      377
Female difference      105
Fetal gene program      84
Fibroblast      142 167 295 344
Fingerprinting      260 298
Fluorescent dye      107 216
Fluorescent dye, Cy3      68 136
Fluorescent dye, Cy5      68 136
Fluorophore      see fluorescent dye
Fourier transform ion cyclotron resonance mass spectrometry (FTICR)      367
Fractionation      365
Functional genomics      57 130
Functional proteomics      255 256
Gene ablation      29
Gene expression      3
Gene expression profile      81
Gene expression profiling      157
Gene family      75
Gene network      57
Gene profiling      81 85 109
Genomic online databases (GOLD)      173
Genotype-phenotype correlation studies      344
Global internal standard technology (GIST)      366
Glycosylation      173
Growth factors      100 142
Heart disease, angiotensin induced      20
Heart disease, isoproterenol induced      20
Heart disease, myocardial infarction      20
Heart disease, transgenic anima      20
Heart failure (HF)      317 370 377
Heart failure (HF), diastolic      45
Heart failure (HF), gene mutations      48
Heart failure (HF), mortality rate      61
Heart failure (HF), systolic      45
High performance liquid chromatography (HPLC)      184 218 322
High-throughput      57 127
Housekeeping genes      14 139
HPLC      see high performance liquid chromatography
HPLC/MS      380
HSP90- $\alpha$       310
Human genome      342 359
Human genome consortium      362
Human genome project      154 352
Human studies      105
Hypertrophic cardiomyopathy (HCM)      55 345
Hypertrophy, phenylephrine-induced      376
ICAT      see isotope coded affinity-tagging
Immediate-early gene      100
Immobilized pH gradients (IPG)      175
IN sequence      325
In situ hybridization      148
in-gel rehydration      176
Inducible gene      159
Inducible nitric oxide synthase (iNOS)      100
Infectious diseases      372 381
Inflammation      131 160 373
Inflammatory diseases      380
Ion exchange      332
Ion trap      183
Ischemia      288
Isoelectric focusing (IEF)      174
Isoelectric focusing size exclusion chromatography (IEF-SEC)      237
Isoproterenol      53 376
Isotope coded affinity      366
Isotope coded affinity tagging (ICAT)      213 215 237 294
Isotope coded affinity tagging (ICAT), advantages      222
Isotope coded affinity tagging (ICAT), applications      223
Isotope coded affinity tagging (ICAT), method      221
k-mean analysis      162
Kallikrein-kinin system      348
Laminar shear stress      160
Langendorff heart perfusion      288
Largescale SNP/haplotype association studies      344
Laser microdissection      145
Laser-assisted micro-dissection      168
LC/MS/MS      202 298
Lead identification      343
Lead validation      343 351
Liquid chromatography (LC)      196
Low-density lipoproteins (LDL)      307
Macrophage      167
MALDI      see matrix-assisted laser desorption/ionization
MALDI Q-TOF      366
MALDI-TOF      see matrix assisted Laser desorption/ionization-time of flight
MALDI-TOF MS      294 312
Male difference      105
Mass spectrometry (MS)      180 259 341
Mass spectrometry (MS), b and y ions      201
Mass spectrometry (MS), fingerprint      183
Mass spectrometry (MS), ionization      195
Mass spectrometry (MS), mass profile      183
Mass spectrometry (MS), precursor ion      197
Mathematical modelling      144
Matrix assisted laser desorption/ionization tandem mass spectrometer (MALDI-MS)      229 284
Matrix assisted laser desorption/ionization-time of flight (MALDI-TOF)      180
Matrix assisted laser desorption/ionization-time of flight (MALDI-TOF), post-source decay (PSD)      184
Matrix metalloproteinases (MMP)      48
Matrix-assisted laser desorption/ionization (MALDI)      183 259
Membrane proteins      223
Metabolically labeled      221
Metabolism-targeted      294
Microarray Gene Expression Database (MGED)      19
Microarray, advantage      33 63
Microarray, artifacts      65
Microarray, data analysis      11 36 69
Microarray, design experiments      9
Microarray, disadvantage      9 33
Microarray, experimental design      63 64 65
Microarray, fluorescent dyes/fluorophore      66
Microarray, front-end      36
Microarray, homogeneity      10
Microarray, limitations      73
Microarray, misidentified cDNA      122
Microarray, non-fluorescent dyes      66
Microarray, replicate      66
Microarray, replication      10
Microarray, reporting error      122
Microarray, resources      34 35 40
Microarray, RNA amplification      67
Microarray, RNA stabilization      66

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