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Авторизация |
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Поиск по указателям |
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Van Eyk J.E., Dunn M.J. — Proteomic and genomic analysis of cardiovascular disease |
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Предметный указатель |
Microarray, RNase 67
Microarray, sequencing 88
Microarray, signal noise ratio 35
Microarray, spotting error 118
Microarray, time courses 10
Microarray, website 127
Microfabrication 242
Microsomal 223
Mitochondria 279 288
Mitochondrial () 284
Mitochondrial genome 90
MLC-1 see myosin light chain 1
Molecular imprinting 241
Monocyte 167
MS/MS 197 260 284 294
MudPIT 367
Multi-dimensional liquid chromatography (MDLC) 204 237 287
Multidimensional protein identification technology (MudPIT) 367
Myocardial biopsy 61
Myocardial energetics 49
Myocardial infarction 45 141
Myocardial ischemia 91
Myocardial stunning 91
Myofibril preparation 325 326
Myofilament proteins 319 320 322
myosin 28 323
Myosin heavy chain 350
Myosin light chain (MLC20) 263
Myosin light chain 1 (MLC-1) 320 322
Narrow-range pH gradients 177 178
Natriuretic peptide, ANP 20
Natriuretic peptide, BNP 20
Neonatal rat cardiomyocytes 370
Neurological diseases 379
NF-kB 142
Nitrovasodilator 265
Nonfluorescent dye biotin 68
Northern blotting 116
Novel candidate targets 360
Novel genes 93
NP-40 174
Nuclear peroxisome proliferator activator receptor (PPAR) 374
Nuclear protein 179 225
Nucleic acid array 243
Nucleotide 52
Nucleotide polymorphism 52
Obese rats 134
Oligonucleotide arrays 3 130
Oligonucleotide microarray, affymetrix 8
Oligonucleotide microarray, invitrogen 113
Oligonucleotide microarray, protocol 8
Organelle 300
P13K/AKT 103
Peptide mass fingerprinting (PMF) 183
Pharmacogenetics 341
Phosphatase and tensin homologue on chromosome ten (PTEN) 36
Phosphor imaging 183
Phosphorylation 84 205 239 279 289
Plaque 141
Plasminogen activator inhibitor-1 (PAI-1) 92
Platelet derived growth factor (PDGF) 142 307
Polymorphism 52
Polysome 36
Positional cloning 27
Post-transcriptional 294
Post-transcriptional modification (PTM) 108
Post-translational 286 318
Pre-clinical evaluation 360
Preconditioning 99
Preparation of samples 290
Protein arrays 238
Protein arrays, antibody 299
Protein arrays, recombinant 299
Protein Chips 368
Protein complexes 295 299
Protein detection 330
Protein detection, coomassie brilliant blue 179
Protein detection, different colour 332
Protein detection, fluorescence 180
Protein detection, linear range 331
Protein detection, problematic 332
Protein detection, radiolabelling 182
Protein detection, sensitivity 331
Protein detection, silver staining 180
Protein detection, Sypro Orange 180
Protein detection, Sypro Red 180
Protein detection, Sypro Ruby 180
Protein identification 183
Protein identification, cross-species protein 188
Protein identification, sequence tag 184
Protein identification, strategies 199
Protein identification, western blot 229
Protein kinase 99
Protein kinase C (PKC) 296
Protein kinase C (PKC) 279 293
Protein network maps 362
Protein recognition molecule (PRM) 239
Protein recognition molecule (PRM), detection 244
Protein recognition molecule (PRM), immobilisation strategy 242
Protein recognition molecule (PRM), requirements 239
Protein recognition molecule (PRM), sensitivity 241
Protein signature 373
Protein solubilization 174
Proteoglycan 166
Proteolysis 189
| PTM 322
PTM, identification 205
Pulmonary artery 162
Pulmonary systemic 156
Quadrupole 183
Quadrupole time-of-flight (Q-TOF) 183
Quarts crystal microbalance (QCM) 244
Reactive oxygen species (ROS) 49 307
Renin-angiotensin-aldosterone system (RAAS) 348
ResGen rat 113
Resources 133 165 173 187
Resources, 2DE databases 262
Resources, DNA genome 344
Resources, microarray 6
Resources, website 186
Reverse genetics 27 344
Reversed-phase 332
Ribosomal protein 179
RT-PCR (real time reverse transcription polymerase chain reaction) 89 108 143 163
RT-PCR analysis 51
Sarcomeric proteins 27
SDS see sodium dodecyl sulfate
SDS-PAGE see sodium dodecyl sulfate PAGE
Secreted oxidative stress induced factor (SOXF) 307 308 310 371
SELDI see surface enhanced laser desorption/ionization
SELDI-TOF 368 376
Sensitivity 204
sequencing 88
SERCA (-ATPase) 90
Serial analysis of gene expression (SAGE) 29 173
Signal transduction 186 293 303
Silver staining 235 330
Single nucleotide polymorphism (SNP) 341 343 352 361
Skeletal muscle 317
Skeletal muscle nemaline myopathy (NM) 321
Skeletal muscle, fiber types 318
Skeletal muscle, isoforms 319
Smooth muscle cell (SMC) 114 255 263 269 371
Sodium dodecyl sulfate (SDS), polyacrylamide gels 175
Sodium dodecyl sulfate (SDS), standard format 176
Sodium dodecyl sulfate PAGE (SDS-PAGE) 214 218 298 310
Sodium dodecyl sulfate PAGE (SDS-PAGE), acrylamide derivative 176
SOXF see secreted oxidal stress induced factor
Stable isotope labeling 218
Statins 350
Stress response 82
Stress-related genes 101
Structural proteomics 257
Subcellular locations 300
Subproteome 179 298 313 323
Subproteome, identification 297
Subproteome, isolation 297
Subproteome, separation 297
Subproteome, substrate profiling 267
Subproteome, subtraction suppression hybridization (SSH) 127
Subproteome, subtractive hybridization 84 85
Surface enhanced laser desorption/ionization (SELDI) 237 332 378
Surface plasmon resonance (SPR) 244
Synthetic carrier ampholytes (SCA) 175
SYPRO dyes 298
Systemic 154 ff
Tandem affinity purification (TAP) 235
Tangier disease 347
Target discovery see target identification
Target identification 343 361 369
Target validation 343 347 361 362 373
Therapeutic strategies 23
TOF-MS 259
Toxicoproteomics 375
Transcriptional profiling 39
Transgenesis 29
Transgenesis, cre/lox system 31
Transgenesis, E. coli bacteriophage P1 31
Transgenesis, gene targeting 31
Transgenesis, strain dependency 32
Transgenesis, tet-off system 31
Transgenesis, transcriptome analysis 31
Transgenesis, transgene 30
Transgenic 361
Transgenic model 104
Transplantation 106
Troponin I 319
Troponin I SERCA 51
Tumor necrosis factor (TNF) 148
Two-dimensional gel electrophoresis 168 283
Two-dimensional gel electrophoresis, difference gel electrophoresis (2D-DIGE) 236
Two-dimensional gel electrophoresis, disadvantages 236
Two-dimensional gel electrophoresis, fluorescence 235
Two-dimensional gel electrophoresis, limitations 323 327
Two-dimensional gel electrophoresis, silver staining 236
Two-dimensional gel electrophoresis, Sypro ruby 236
Two-dimensional polyacrylamide gel electrophoresis (2DE-PAGE) 173 365 380
Two-dimensional polyacrylamide gel electrophoresis (2DE-PAGE), limitation 258
Two-dimensional polyacrylamide gel electrophoresis (2DE-PAGE), technical difficulties 214
Ubiquitin-proteosome 188
Umbilical vein 160
Under microarray reproducibility 84
Vascular smooth muscle cell (VSMC) 307 371
Vena cava 137
Venn diagram 134
Ventricular assist device 78
VSMC see vascular smooth muscle cell
Western blot-direct serum analysis (WB-DSA) 229 333
Yeast 222
Zoom gels see narrow target pH gradient
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