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| Nathanson N. (ed.), Ahmed R., Brinton M.A. — Viral Pathogenesis and Immunity |
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| Предметный указатель |
Sex differences, virus susceptibility 168
Shedding, virus, environmental survival of shed virus 22
Shedding, virus, fluids 22
Shedding, virus, gastrointestinal tract 21
Shedding, virus, mucous membrane 22
Shedding, virus, oropharynx 21
Shedding, virus, respiratory tract 21—22
Shedding, virus, skin 22
Simian immunodeficiency virus (SIV), antigenic variants 122—123
Simian immunodeficiency virus (SIV), cell killing in vitro 173—174
Simian immunodeficiency virus (SIV), cell killing in vivo 174
Simian immunodeficiency virus (SIV), cellular immune response 177
Simian immunodeficiency virus (SIV), clearance 94f
Simian immunodeficiency virus (SIV), comparative pathogenesis of virulent and attenuated viruses 108
Simian immunodeficiency virus (SIV), glycosylation and immune response 206 206t
Simian immunodeficiency virus (SIV), human immunodeficiency virus chimera, tropism 36—37 36f
Simian immunodeficiency virus (SIV), human immunodeficiency virus chimera, vaccination studies 204—206 208f
Simian immunodeficiency virus (SIV), humoral immune response 177 206f
Simian immunodeficiency virus (SIV), kinetics of infection 179f
Simian immunodeficiency virus (SIV), nonpathogenic infection 180—182
Simian immunodeficiency virus (SIV), persistence 119 122—123
Simian immunodeficiency virus (SIV), species susceptibility 171
Simian immunodeficiency virus (SIV), spread of infection 174
Simian immunodeficiency virus (SIV), strain effects on immunosuppression 93—94
Simian immunodeficiency virus (SIV), susceptibility factors 165f
Simian immunodeficiency virus (SIV), vaccination 205f 206f 208f
Simian immunodeficiency virus (SIV), viral set point 205f
Simian immunodeficiency virus (SIV), virulence and long-term infection 18 If
Sindbis virus, age effects on susceptibility 166
Sindbis virus, apoptosis induction 47
SIV See Simian immunodeficiency virus
Skin, entry of viruses 13—15 15t
Skin, shedding of viruses 22
Skin, structure 12—13
Smoldering infection, definition 120
Smoldering infection, diseases 128
Smoldering infection, persistence mechanisms, antigenic variation 121—123
Smoldering infection, persistence mechanisms, cytotoxic T lymphocyte impairment 121
Smoldering infection, persistence mechanisms, immune-privileged sites 120—121
Smoldering infection, persistence mechanisms, infectious immune complexes 121
Smoldering infection, persistence mechanisms, intercellular bridges 121
Smoldering infection, persistence mechanisms, major histocompatibility complex class I suppression 121
Spallanzani, Lazaro 3
Spread, viruses, blood to tissue spread 19—20
Spread, viruses, human immunodeficiency virus 174
Spread, viruses, local spread 17
Spread, viruses, neural spread 20—21
Spread, viruses, viremia, cell-associated viremia 19
Spread, viruses, viremia, phases 17
Spread, viruses, viremia, plasma viremia 18
Spread, viruses, viremia, sources 18
Src, cellular homolog discovery 10s
Src, viral oncogene 134
SSPE See Subacute sclerosing panencephalitis
St. Louis encephalitis virus, age effects on susceptibility 167—168
SU, CD4 binding 171 172f 177
Subacute sclerosing panencephalitis (SSPE), incidence 127
Subacute sclerosing panencephalitis (SSPE), intercellular bridges in persistence 121
Subacute sclerosing panencephalitis (SSPE), measles virus persistence 127 127f
Susceptibility, age factors 166s
Susceptibility, age factors, infancy 165—167 166f 167t
Susceptibility, age factors, old age 167—168 167f
Susceptibility, human immunodeficiency virus, AIDS resistance 164—165
Susceptibility, human immunodeficiency virus, HLA-B57 in AIDS susceptibility 165
Susceptibility, human immunodeficiency virus, infection resistance 164
Susceptibility, mouse models, avian leukosis-sarcoma viruses 162
Susceptibility, mouse models, Flv with flavivirus infection 160—161 161t 162f
Susceptibility, mouse models, loci in mouse strains 160t
Susceptibility, mouse models, lymphocytic choriomeningitis virus 162—163
Susceptibility, mouse models, mouse hepatitis virus receptors 162
Susceptibility, mouse models, murine leukemia virus 161—164
Susceptibility, mouse models, Mx role with influenza virus infection 159—160 161f
Susceptibility, mouse models, overview 158—159
Susceptibility, mouse models, receptors 163t
Susceptibility, mouse models, strain susceptibility 159t 160f 161t 162f
Susceptibility, pregnancy 168
Susceptibility, prospects for study 168
Susceptibility, sex differences 168
Susceptibility, undernutrition 168
SV40, oncogenesis, tumor suppressor protein inactivation 143
Syncytium, virus production 39 39f
T cell See also CD4 lymphocyte; CD8 lymphocyte
T cell receptor (TCR), ligand binding 57 58
T cell receptor (TCR), structure 57
T cell, assays 64t
T cell, assays, chromium-51 release assay 63f: 64
T cell, assays, ELISPOT 65
T cell, assays, fluorescence-activated cell sorting 64—65
T cell, assays, limiting dilution assay 63—64
T cell, immune response overview 57 60f
T cell, kinetics of response 66f
T cell, maturation 56 58—59
T cell, mucosal immune response 67—68
T cell, protection against reinfection 66
T cell, recovery from initial infection 66
T cell, specificity of response 57—58
T cell, virus response, overview 48 117
TCR See T cell receptor
Theiler's murine enephalomyelitis virus (TMEV), classification 126
Theiler's murine enephalomyelitis virus (TMEV), persistence mechanisms 126 126t
TMEV See Theiler's murine enephalomyelitis virus
TMV See Tobacco mosaic virus
TNF See Tumor necrosis factor
Tobacco mosaic virus (TMV), history of study 5
Tolerance, high-titer persistent infections and immune tolerance, lytic viruses 119
Tolerance, high-titer persistent infections and immune tolerance, nonlytic viruses 117—119
Tolerance, lymphocytic choriomeningitis virus induction 85—86
| Tolerance, virus induction features 18 84
Transcription, virus modulation 40—41
Translation, virus modulation 41—2
Transmission, virus entry sites, gastrointestinal tract 15—16
Transmission, virus entry sites, modes 22
Transmission, virus entry sites, oropharynx 15—16
Transmission, virus entry sites, respiratory tract 16—17
Transmission, virus entry sites, skin and mucous membrane 12—15
Transmission, virus entry sites, transcutaneous injection 15
Transmission, virus entry sites, urogenital tract 15
Tropism, cellular receptor, glycoprotein receptors 27—28
Tropism, cellular receptor, herpes simplex virus 26—27 28
Tropism, cellular receptor, human immunodeficiency virus 26 28
Tropism, cellular receptor, nonprotein receptors 28
Tropism, cellular receptor, viral attachment protein binding 25—26 28—29
Tropism, definition 12 25
Tropism, determinants 32s
Tropism, determinants, acid lability 33
Tropism, determinants, cellular receptors 30—32
Tropism, determinants, proteases 32 33
Tropism, determinants, temperature sensitivity 33
Tropism, determinants, transcriptional control 33—34
Tropism, lymphocytic choriomeningitis virus 32
Tropism, parvovirus B19 31—32
Tropism, poliovirus 30—31
Tropism, retrovirus 34—35
Tropism, variation and pathogenicity 35—37
Tumor necrosis factor (TNF), poxvirus viroceptors 112
Urine, shedding of viruses 22
Urogenital tract, viral entry 15
Vaccination, AIDS See Human immunodeficiency virus
Vaccination, DNA vaccines 195—196
Vaccination, historical perspectives 189
Vaccination, immune induction principles 190s
Vaccination, inactivated viruses, denaturation 193
Vaccination, inactivated viruses, efficacy 193—194
Vaccination, inactivated viruses, recombinant proteins 194
Vaccination, inactivated viruses, safety 194
Vaccination, licensed human vaccines 190 192t 196
Vaccination, live attenuated virus, efficacy 190—192
Vaccination, live attenuated virus, safety 192—193
Vaccination, live attenuated virus, tropism 190
Vaccination, modalities, advantages and disadvantages 190 191t
Vaccination, modalities, overview 189—190 208
Vaccination, principles of immune induction relevant for efficacy 189—190
Vaccination, protective mechanisms, hepatitis B 200—203
Vaccination, protective mechanisms, polio 192t 196—198 197f 198f 198t
Vaccination, protective mechanisms, principles 196 197s 208
Vaccination, protective mechanisms, rabies 198—200
Vaccination, recombinant virus vaccines 194—195
Vaccination, replicons 195
Vaccinia virus, complement cascade interference 87 88f 112
Vaccinia virus, immunosuppression in mice 86t
Vaccinia virus, recombinant virus vaccines 195
VAP See Viral attachment protein
Varicella-zoster virus (VZV), age effects on susceptibility 168
Varicella-zoster virus (VZV), latency 119—120
Viral attachment protein (VAP), cellular receptor binding 25—26 26f 28—29
Viral attachment protein (VAP), mutagenesis studies 36f
Viremia, acute viremia 18f
Viremia, blood to tissue pathway 19—20 20f
Viremia, cell associated viremia 17f 19 19t
Viremia, comparative pathogenesis of virulent and attenuated viruses 105
Viremia, human immunodeficiency virus 174—175
Viremia, phases 17
Viremia, plasma viremia 18
Viremia, potential and pathogenicity 105f 106f
Viremia, sources 18
Virulence, approaches to study 99—100
Virulence, attenuated variant virus selection, choice of viruses for virulence studies 104
Virulence, attenuated variant virus selection, cold-adapted variants 103—104 104t
Virulence, attenuated variant virus selection, monoclonal antibody-resistant viruses 104
Virulence, attenuated variant virus selection, mutagenized viruses 104
Virulence, attenuated variant virus selection, temperature-sensitive mutants 103
Virulence, cellular virulence genes, herpes simplex virus Fc receptors 112—113
Virulence, cellular virulence genes, overview 111—112
Virulence, cellular virulence genes, poxviruses 112
Virulence, comparative pathogenesis of virulent and attenuated viruses 0
Virulence, comparative pathogenesis of virulent and host immune response 108
Virulence, comparative pathogenesis of virulent and neural spread 105 106
Virulence, comparative pathogenesis of virulent and portal of entry 105
Virulence, comparative pathogenesis of virulent and target organ 106 107t
Virulence, comparative pathogenesis of virulent and tissue specificity 107—108
Virulence, comparative pathogenesis of virulent and viremia 105
Virulence, definition 99
Virulence, genetic determinants, bunyavirus 107f 109
Virulence, genetic determinants, molecular determination 111t
Virulence, genetic determinants, overview 108—109 109s
Virulence, genetic determinants, poliovirus 109—111
Virulence, genetic determinants, reovirus 109
Virulence, measures, case / infection ratio 100t 102
Virulence, measures, case fatality rate 101t 102
Virulence, measures, incubation period 100—101
Virulence, measures, Lesions 101 101f
Virulence, measures, plaque-forming unit assays 101 101f
Virulence, measures, symptoms 100
Virulence, passage in experimental manipulation, animals 102
Virulence, passage in experimental manipulation, cell culture 102
Virulence, passage in experimental manipulation, viral phenotype 102—103
Virulence, relative nature 100
Virus, origins of word 6s
VZV See Varicella-zoster virus
West Nile virus (WNV), Flv and susceptibility in mice 16
West Nile virus (WNV), immunosuppression studies 117f
Western blot, antibody assay 60—61 61f
WNV See West Nile virus
Yellow fever, history of study 6
Yellow fever, vaccine contamination 192—193 194f
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