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Àâòîðèçàöèÿ |
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Ïîèñê ïî óêàçàòåëÿì |
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Nathanson N. (ed.), Ahmed R., Brinton M.A. — Viral Pathogenesis and Immunity |
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Ïðåäìåòíûé óêàçàòåëü |
Human T-cell lymphotrophic virus type 1 (HTLV-I), accessory gene transactivation in oncogenesis 135 138—139
Human T-cell lymphotrophic virus type 1 (HTLV-I), cellular targeting 139
Human T-cell lymphotrophic virus type 1 (HTLV-I), epidemiology 138—139
Human T-cell lymphotrophic virus type 1 (HTLV-I), transcription regulation 41
Human T-cell lymphotrophic virus type 1 (HTLV-I), transforming action 139f
IgA See Immunoglobulin A
IL-4 See Interleukin-4
Immunoglobulin A (IgA), inactivated virus vaccine induction 194
Immunoglobulin A (IgA), virus defense 14
Immunoglobulin assays, ELISPOT 61 63
Immunoglobulin assays, enzyme-linked immunosorbent assay 60
Immunoglobulin assays, plaque reduction neutralization test 60 61f
Immunoglobulin assays, Western blot 60—61 61f
Immunoglobulin, classes 62f
Immunoglobulin, effector functions 61—62
Immunoglobulin, escape mutant selection 122f 123f
Immunoglobulin, infectious immune complexes in persistence 121
Immunoglobulin, kinetics of response 62—63
Immunoglobulin, monoclonal antibody-resistant viruses 104
Immunoglobulin, mucosal immune response 67—68 68t
Immunoglobulin, natural antibody, host defense 56
Immunoglobulin, neutralizing activity 62 62t
Immunoglobulin, poliovirus clearance 117
Immunoglobulin, protection against reinfection 67 67f
Immunopafhology, virus-induced, antibody-mediated immunopathology, clinical disease 7 It 77—78
Immunopafhology, virus-induced, antibody-mediated immunopathology, experimental examples 76—77
Immunopafhology, virus-induced, autoimmune disease 78—80
Immunopafhology, virus-induced, cell-mediated immunopathology, clinical disease 73—76
Immunopafhology, virus-induced, cell-mediated immunopathology, experimental examples 72—73
Immunopafhology, virus-induced, cell-mediated immunopathology, mechanisms 70—72
Immunopafhology, virus-induced, cell-mediated immunopathology, protective versus pathogenic effects on immune response 70 71t 80
Immunosuppression, virus induction, animal viruses 88—91
Immunosuppression, virus induction, determinants, administration route 94
Immunosuppression, virus induction, determinants, age of host 94
Immunosuppression, virus induction, determinants, immunosuppression therapy 94
Immunosuppression, virus induction, determinants, inoculum size 94
Immunosuppression, virus induction, determinants, strains 93—94
Immunosuppression, virus induction, human immunodeficiency virus See Human immunodeficiency virus
Immunosuppression, virus induction, human viruses 89t 91—93
Immunosuppression, virus induction, mechanisms 83t
Immunosuppression, virus induction, mechanisms, cellular attack 83—84
Immunosuppression, virus induction, mechanisms, overview 82 83t 94—95
Immunosuppression, virus induction, mechanisms, tolerance induction 84—86
Immunosuppression, virus induction, mechanisms, viral protein inhibitors 86—88
Influenza A virus, cellular receptor 28—30
Influenza A virus, entry in cells 29 3
Influenza A virus, M2 ion channel activity 45
Interferon, biological activity 53 54f
Interferon, classification 53—54
Interferon, host defense mechanisms 55
Interferon, Mx induction 159—160
Interferon, poxvirus mimicry of receptors 88
Interferon, properties 54t
Interferon, receptors and signaling 54—55 89f
Interferon, virus induction 53 55 56f
Interleukin-4 (IL-4), poxvirus virulence factor 112
Internal ribosome entry site (IRES), poliovirus utilization 42 42f
IRES See Internal ribosome entry site
JAK-STAT signaling, interferons 54—55
Kaposi's sarcoma, AIDS association 152
Kaposi's sarcoma, etiology See Human herpesvirus 8
Kaposi's sarcoma, histopathology 152
Kaposi's sarcoma, history of study 152 153t
Kidney, immune surveillance evasion by viruses 120
La Crosse virus, virulence, assay 100 102 105
La Crosse virus, virulence, genetic determinants 109
La Crosse virus, virulence, reassortant viruses 11 Of
La Crosse virus, virulence, virulence, passage effects 102t
La Crosse virus, virulence, virulence, temperature-sensitive mutants 103f
La Crosse virus, virulence, virulence, variants and virulence 100t
La Crosse virus, virulence, virulence, viremia and virulence 106f
LCMV See Lymphocytic choriomeningitis virus
LDA See Limiting dilution assay
Lentivirus, features 170—171
Lentivirus, types 171
Limiting dilution assay (LDA), cellular immunity assay 63—64
Lister, antiseptic studies 4
LMP1; oncogenesis role 150—151
Lymphocytic choriomeningitis virus (LCMV), age effects on susceptibility 165
Lymphocytic choriomeningitis virus (LCMV), antibody response 63f
Lymphocytic choriomeningitis virus (LCMV), antibody-mediated immunopathology 77 79f
Lymphocytic choriomeningitis virus (LCMV), antigenic variants 122
Lymphocytic choriomeningitis virus (LCMV), cell-mediated immunopathology 72—73 72s 73f
Lymphocytic choriomeningitis virus (LCMV), comparative pathogenesis of virulent and attenuated viruses 108
Lymphocytic choriomeningitis virus (LCMV), focal tissue destruction 75f
Lymphocytic choriomeningitis virus (LCMV), growth hormone effects 41f
Lymphocytic choriomeningitis virus (LCMV), immune complex deposition in kidney 77f
Lymphocytic choriomeningitis virus (LCMV), immune escape 124f
Lymphocytic choriomeningitis virus (LCMV), immunosuppression induction 84f 85t 86f 86t 94f
Lymphocytic choriomeningitis virus (LCMV), immunosuppression induction, age of host effects 94
Lymphocytic choriomeningitis virus (LCMV), immunosuppression induction, cellular targets 83—84 89t
Lymphocytic choriomeningitis virus (LCMV), immunosuppression induction, strain specificity 88—89 93
Lymphocytic choriomeningitis virus (LCMV), immunosuppression induction, tolerance induction 85—86
Lymphocytic choriomeningitis virus (LCMV), perforin knockout effects 74f
Lymphocytic choriomeningitis virus (LCMV), persistence 114 118 119 122
Lymphocytic choriomeningitis virus (LCMV), replication 39f
Lymphocytic choriomeningitis virus (LCMV), susceptibility factors 162—163
Lymphocytic choriomeningitis virus (LCMV), transcription regulation 40 41t
Lymphocytic choriomeningitis virus (LCMV), tropism and cellular receptor 32
M cell, reovirus endocytosis 15
M2; ion channel activity 45
Macrophage, lymphocytic choriomeningitis virus targeting 83—84 89
Major histocompatibility complex (MHC), antigen processing 43^44 48
Major histocompatibility complex (MHC), HLA-B57 in AIDS susceptibility 165 165t 183
Major histocompatibility complex (MHC), mouse susceptibility role 163f 164f
Major histocompatibility complex (MHC), virus modulation of class I molecule expression 43^15 87—88 121
MBP See Myelin basic protein
MCFV See Mink cell focus-forming virus
Mean transit time (), measurement 18 19s
Measles virus, age effects on susceptibility 5t 167 168
Measles virus, epidemiology 127
Measles virus, genome and proteins 127
Measles virus, immunosuppression induction, discovery 82
Measles virus, immunosuppression induction, kinetics 83f 91
Measles virus, immunosuppression induction, mechanisms 91
Measles virus, P3 mimicry of corticotropin 80t
Measles virus, perpetuation 23 23t
Measles virus, persistence mechanisms 127
Measles virus, smoldering infection See Subacute sclerosing panencephalitis
Measles virus, T cell effects 91f
MHC See Major histocompatibility complex
Milk, shedding of viruses 22
Mims, Cedric 12
Mink cell focus-forming virus (MCFV), classification 135
Mink cell focus-forming virus (MCFV), oncogenesis 136—137
Mos, viral oncogene 134
Mouse hepatitis virus, receptors in susceptibility 162
Mucosal immune response, virus infection 67—68 68t
Mucous membrane, entry of viruses 13—15 15t
Mucous membrane, shedding of viruses 22
MuLV See Murine leukemia virus
Murine leukemia virus (MuLV), classification 135 136t
Murine leukemia virus (MuLV), immunosuppression induction 90—91
Murine leukemia virus (MuLV), murine AIDS features 90
Murine leukemia virus (MuLV), oncogenesis, insertional mutagenesis 132—133 135—136
Murine leukemia virus (MuLV), oncogenesis, strain specificity 136
Murine leukemia virus (MuLV), susceptibility role, Fv-1 161—162
Murine leukemia virus (MuLV), susceptibility role, major histocompatibility complex associated genes 163—164
Mx, influenza susceptibility role 159—160
Mx, interferon induction 159—160
Myb, viral oncogene 134
Myelin basic protein (MBP), molecular, mimicry by viruses 79
Natural antibody, host defense 56
Natural killer (NK) cell, antibody modulation 62
Natural killer (NK) cell, cell-mediated immunopathology role 71
Natural killer (NK) cell, cytoplasmic granules 55
Natural killer (NK) cell, host defense mechanisms 55
Natural killer (NK) cell, receptors 55
Necrosis, features 45—46
Necrosis, virus induction 46
| Nef, downregulation of major histocompatibility complex 44
Neural spread, comparative pathogenesis of virulent and attenuated viruses 105—106
Neural spread, viruses 20—21
Newcastle disease virus, proteolytic activation of fusion protein 32—33 33f
NK cell See Natural killer cell
Oncogenesis, DNA viruses, adenovirus 148 -150
Oncogenesis, DNA viruses, Epstein — Barr virus 150—152
Oncogenesis, DNA viruses, human herpesvirus 8 152—154
Oncogenesis, DNA viruses, human papillomavirus 144—148
Oncogenesis, DNA viruses, tumor suppressor protein inactivation 142—144
Oncogenesis, DNA viruses, virus types 142 143t
Oncogenesis, retrovirus, accessory gene transactivation 135
Oncogenesis, retrovirus, avian leukosis-sarcoma viruses 137—138
Oncogenesis, retrovirus, cellular specificity of tumors 139—140
Oncogenesis, retrovirus, classification of viruses by mechanism 131—132 132t
Oncogenesis, retrovirus, common mechanistic themes 135
Oncogenesis, retrovirus, human T-cell lymphotrophic virus type I 135 138—139 139f
Oncogenesis, retrovirus, insertional mutagenesis by nonacute transforming viruses 132—133
Oncogenesis, retrovirus, mink cell focus-forming virus 136—137
Oncogenesis, retrovirus, molecular determinants 140s
Oncogenesis, retrovirus, multistep tumorigenesis 132 140 1401'
Oncogenesis, retrovirus, murine leukemia virus 132- 133 135—136 136t 137f
Oncogenesis, retrovirus, nonacute transforming retrovirus 133f
Oncogenesis, retrovirus, oncogenes and acute transformation 133—135 134f 134t
Oncogenesis, retrovirus, Rous sarcoma virus 137—138 138t
Oncogenesis, retrovirus, virus types 130 130t 131
Oropharynx, entry of viruses 15—16
Oropharynx, shedding of viruses 21
p53; cell cycle control 144
p53; mutations in cancer 144
p53; virus inactivation in oncogenesis 143—144 150
Panum, Peter 3
Parvovirus B19; age effects on susceptibility 166
Parvovirus B19; tropism and cellular receptor 31—32
Pasteur, L. 3
Pathogenicity See Virulence
Persistence, cell culture models, lytic viruses 115 116t
Persistence, cell culture models, nonlytic viruses 114—115 116t
Persistence, cell culture models, variation in virus and cells 116
Persistence, diseases with persistent infection 115t 127—128 128t
Persistence, genetic determinants 116t
Persistence, herpes simplex virus 124—126
Persistence, high-titer persistent infections and immune tolerance, lytic viruses 119
Persistence, high-titer persistent infections and immune tolerance, nonlytic viruses 117—119
Persistence, human immunodeficiency virus 178
Persistence, latent infection 119—120 124—126
Persistence, measles virus 127
Persistence, mechanisms, overview 114 115t
Persistence, patterns 118f
Persistence, rules in vivo 115s
Persistence, smoldering infection persistence mechanisms, antigenic variation 121—123
Persistence, smoldering infection persistence mechanisms, cytotoxic T lymphocyte impairment 121
Persistence, smoldering infection persistence mechanisms, immune-privileged sites 120—121
Persistence, smoldering infection persistence mechanisms, infectious immune complexes 121
Persistence, smoldering infection persistence mechanisms, intercellular bridges 121 121f
Persistence, smoldering infection persistence mechanisms, major histocompatibility complex class I suppression 121
Persistence, T cell clearance 118f
Persistence, Theiler's murine enephalomyelitis virus 126
pl5E, reduction of T cell proliferation 87
Poliovirus, age effects on susceptibility 166
Poliovirus, antibody protection 197 198t
Poliovirus, eradication 197—198
Poliovirus, excretion 21f
Poliovirus, history of study 6—7
Poliovirus, inactivated virus vaccine 193 197
Poliovirus, oral polio vaccine, attenuation 9—10 100 193t
Poliovirus, oral polio vaccine, efficacy 190—192 197
Poliovirus, oral polio vaccine, safety 192—193 198
Poliovirus, oral polio vaccine, tropism 2It 190 192t
Poliovirus, pathogenesis 196f
Poliovirus, receptor expression 32t
Poliovirus, replication 39f
Poliovirus, spread 13f
Poliovirus, translational modulation 41—12
Poliovirus, tropism and cellular receptor 30—31
Poliovirus, tropism of strains 20 21
Poliovirus, vaccine development 8s 9 197
Poliovirus, viremia 18f
Poliovirus, virulence, comparative pathogenesis of virulent and attenuated viruses 105 106
Poliovirus, virulence, genetic determinants 109—111
Poliovirus, virulence, pathogenesis 196—197
Poliovirus, virulence, VP2 mimicry of acetylcholine receptor 80t
Polyoma virus, VP1 interactions with receptor 35—36
Pregnancy, virus susceptibility factor 168
Programmed cell death See Apoptosis
Rabiesvirus, history 3 4f
Rabiesvirus, incubation period 199
Rabiesvirus, mimicry of insulin receptor 80t
Rabiesvirus, neural spread, comparative pathogenesis of virulent and attenuated viruses 105—106
Rabiesvirus, passage and virulence 106t
Rabiesvirus, pathogenesis 198—199
Rabiesvirus, spread 14f
Rabiesvirus, vaccination, CD8 cell response 200
Rabiesvirus, vaccination, immune-mediated disease enhancement 200
Rabiesvirus, vaccination, postexposure immunization 199—200 200f 200t
Rabiesvirus, vaccination, preexposure prophylaxis 199 199t
Ras, viral oncogene 134
Rb See Retinoblastoma protein
Reed, Walter 6
Reovirus, apoptosis induction 39—40 40t
Reovirus, comparative pathogenesis of virulent and attenuated viruses 107
Reovirus, persistence 116
Reovirus, proteolytic activation 34f
Reovirus, reassortant viruses 1 lOt
Reovirus, virulence, genetic determinants 109
Replication, viral burden on host translation machinery 38
Replicon, vaccine utilization 195
Respiratory syncytial virus (RSV), cell-mediated immunopathology 73
Respiratory tract, entry of viruses 16—17 16t
Respiratory tract, shedding of viruses 21—22
Retinoblastoma protein (Rb), cell cycle control 143—144
Retinoblastoma protein (Rb), virus inactivation in oncogenesis 143—144 149
Retrovirus, definition 34
Retrovirus, genome and proteins 130 131 132f
Retrovirus, high-titer persistent infection 131
Retrovirus, integration in host genome 131
Retrovirus, oncogenesis, accessory gene transactivation 135
Retrovirus, oncogenesis, avian leukosis-sarcoma viruses 137—138
Retrovirus, oncogenesis, cellular specificity of tumors 139—140
Retrovirus, oncogenesis, classification of viruses by mechanism 131—132 132t
Retrovirus, oncogenesis, common mechanistic themes 135
Retrovirus, oncogenesis, human T-cell lymphotropic virus type 1 135 138—139 139f
Retrovirus, oncogenesis, insertional mutagenesis by nonacute transforming viruses 132—133
Retrovirus, oncogenesis, mink cell focus-forming virus 136—137
Retrovirus, oncogenesis, molecular determinants 140s
Retrovirus, oncogenesis, multistep tumorigenesis 132 140 140f
Retrovirus, oncogenesis, murine leukemia virus 132—133 135—136 136t 137f
Retrovirus, oncogenesis, nonacute transforming retrovirus 133f
Retrovirus, oncogenesis, oncogenes and acute transformation 133—135 134f 134t
Retrovirus, oncogenesis, Rous sarcoma virus 137—138 138t
Retrovirus, oncogenesis, virus types 130 130t 131
Retrovirus, replication 130—131
Retrovirus, structure 130
Retrovirus, tropism factors 34—35
Rhinovirus, temperature sensitivity 33
RNA polymerase, virus modulation 40
Rous sarcoma virus (RSV), classes 138t
Rous sarcoma virus (RSV), endogenous viruses 138
Rous sarcoma virus (RSV), history of study 7 137
Rous sarcoma virus (RSV), oncogenesis 137—138
Rous sarcoma virus (RSV), receptors 138
Rous sarcoma virus (RSV), replication-competent and defective viruses 137—138
Rous sarcoma virus (RSV), src, cellular homolog discovery 10
Rous, Peyton 7
RSV See Respiratory syncytial virus; Rous sarcoma virus
Rubella, immunosuppression induction 92 92f
Rush, Benjamin 3
Saliva, shedding of viruses 22
Semen, shedding of viruses 22
Sendai virus, syncytium production 39
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