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Nathanson N. (ed.), Ahmed R., Brinton M.A. — Viral Pathogenesis and Immunity
Nathanson N. (ed.), Ahmed R., Brinton M.A. — Viral Pathogenesis and Immunity



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Íàçâàíèå: Viral Pathogenesis and Immunity

Àâòîðû: Nathanson N. (ed.), Ahmed R., Brinton M.A.

Àííîòàöèÿ:

Introductory textbook for graduate students and trainees. Treats all aspects of infection of the animal host with emphasis on mechanisms explaining the complex interaction between parasite and host. Keeps only to the essentials. Softcover. DNLM: Viruses — pathogenicity.


ßçûê: en

Ðóáðèêà: Ìåäèöèíà è çäðàâîîõðàíåíèå/

Ñòàòóñ ïðåäìåòíîãî óêàçàòåëÿ: Ãîòîâ óêàçàòåëü ñ íîìåðàìè ñòðàíèö

ed2k: ed2k stats

Ãîä èçäàíèÿ: 2001

Êîëè÷åñòâî ñòðàíèö: 220

Äîáàâëåíà â êàòàëîã: 01.12.2006

Îïåðàöèè: Ïîëîæèòü íà ïîëêó | Ñêîïèðîâàòü ññûëêó äëÿ ôîðóìà | Ñêîïèðîâàòü ID
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Ïðåäìåòíûé óêàçàòåëü
Human T-cell lymphotrophic virus type 1 (HTLV-I), accessory gene transactivation in oncogenesis      135 138—139
Human T-cell lymphotrophic virus type 1 (HTLV-I), cellular targeting      139
Human T-cell lymphotrophic virus type 1 (HTLV-I), epidemiology      138—139
Human T-cell lymphotrophic virus type 1 (HTLV-I), transcription regulation      41
Human T-cell lymphotrophic virus type 1 (HTLV-I), transforming action      139f
IgA      See Immunoglobulin A
IL-4      See Interleukin-4
Immunoglobulin A (IgA), inactivated virus vaccine induction      194
Immunoglobulin A (IgA), virus defense      14
Immunoglobulin assays, ELISPOT      61 63
Immunoglobulin assays, enzyme-linked immunosorbent assay      60
Immunoglobulin assays, plaque reduction neutralization test      60 61f
Immunoglobulin assays, Western blot      60—61 61f
Immunoglobulin, classes      62f
Immunoglobulin, effector functions      61—62
Immunoglobulin, escape mutant selection      122f 123f
Immunoglobulin, infectious immune complexes in persistence      121
Immunoglobulin, kinetics of response      62—63
Immunoglobulin, monoclonal antibody-resistant viruses      104
Immunoglobulin, mucosal immune response      67—68 68t
Immunoglobulin, natural antibody, host defense      56
Immunoglobulin, neutralizing activity      62 62t
Immunoglobulin, poliovirus clearance      117
Immunoglobulin, protection against reinfection      67 67f
Immunopafhology, virus-induced, antibody-mediated immunopathology, clinical disease      7 It 77—78
Immunopafhology, virus-induced, antibody-mediated immunopathology, experimental examples      76—77
Immunopafhology, virus-induced, autoimmune disease      78—80
Immunopafhology, virus-induced, cell-mediated immunopathology, clinical disease      73—76
Immunopafhology, virus-induced, cell-mediated immunopathology, experimental examples      72—73
Immunopafhology, virus-induced, cell-mediated immunopathology, mechanisms      70—72
Immunopafhology, virus-induced, cell-mediated immunopathology, protective versus pathogenic effects on immune response      70 71t 80
Immunosuppression, virus induction, animal viruses      88—91
Immunosuppression, virus induction, determinants, administration route      94
Immunosuppression, virus induction, determinants, age of host      94
Immunosuppression, virus induction, determinants, immunosuppression therapy      94
Immunosuppression, virus induction, determinants, inoculum size      94
Immunosuppression, virus induction, determinants, strains      93—94
Immunosuppression, virus induction, human immunodeficiency virus      See Human immunodeficiency virus
Immunosuppression, virus induction, human viruses      89t 91—93
Immunosuppression, virus induction, mechanisms      83t
Immunosuppression, virus induction, mechanisms, cellular attack      83—84
Immunosuppression, virus induction, mechanisms, overview      82 83t 94—95
Immunosuppression, virus induction, mechanisms, tolerance induction      84—86
Immunosuppression, virus induction, mechanisms, viral protein inhibitors      86—88
Influenza A virus, cellular receptor      28—30
Influenza A virus, entry in cells      29 3
Influenza A virus, M2 ion channel activity      45
Interferon, biological activity      53 54f
Interferon, classification      53—54
Interferon, host defense mechanisms      55
Interferon, Mx induction      159—160
Interferon, poxvirus mimicry of receptors      88
Interferon, properties      54t
Interferon, receptors and signaling      54—55 89f
Interferon, virus induction      53 55 56f
Interleukin-4 (IL-4), poxvirus virulence factor      112
Internal ribosome entry site (IRES), poliovirus utilization      42 42f
IRES      See Internal ribosome entry site
JAK-STAT signaling, interferons      54—55
Kaposi's sarcoma, AIDS association      152
Kaposi's sarcoma, etiology      See Human herpesvirus 8
Kaposi's sarcoma, histopathology      152
Kaposi's sarcoma, history of study      152 153t
Kidney, immune surveillance evasion by viruses      120
La Crosse virus, virulence, assay      100 102 105
La Crosse virus, virulence, genetic determinants      109
La Crosse virus, virulence, reassortant viruses      11 Of
La Crosse virus, virulence, virulence, passage effects      102t
La Crosse virus, virulence, virulence, temperature-sensitive mutants      103f
La Crosse virus, virulence, virulence, variants and virulence      100t
La Crosse virus, virulence, virulence, viremia and virulence      106f
LCMV      See Lymphocytic choriomeningitis virus
LDA      See Limiting dilution assay
Lentivirus, features      170—171
Lentivirus, types      171
Limiting dilution assay (LDA), cellular immunity assay      63—64
Lister, antiseptic studies      4
LMP1; oncogenesis role      150—151
Lymphocytic choriomeningitis virus (LCMV), age effects on susceptibility      165
Lymphocytic choriomeningitis virus (LCMV), antibody response      63f
Lymphocytic choriomeningitis virus (LCMV), antibody-mediated immunopathology      77 79f
Lymphocytic choriomeningitis virus (LCMV), antigenic variants      122
Lymphocytic choriomeningitis virus (LCMV), cell-mediated immunopathology      72—73 72s 73f
Lymphocytic choriomeningitis virus (LCMV), comparative pathogenesis of virulent and attenuated viruses      108
Lymphocytic choriomeningitis virus (LCMV), focal tissue destruction      75f
Lymphocytic choriomeningitis virus (LCMV), growth hormone effects      41f
Lymphocytic choriomeningitis virus (LCMV), immune complex deposition in kidney      77f
Lymphocytic choriomeningitis virus (LCMV), immune escape      124f
Lymphocytic choriomeningitis virus (LCMV), immunosuppression induction      84f 85t 86f 86t 94f
Lymphocytic choriomeningitis virus (LCMV), immunosuppression induction, age of host effects      94
Lymphocytic choriomeningitis virus (LCMV), immunosuppression induction, cellular targets      83—84 89t
Lymphocytic choriomeningitis virus (LCMV), immunosuppression induction, strain specificity      88—89 93
Lymphocytic choriomeningitis virus (LCMV), immunosuppression induction, tolerance induction      85—86
Lymphocytic choriomeningitis virus (LCMV), perforin knockout effects      74f
Lymphocytic choriomeningitis virus (LCMV), persistence      114 118 119 122
Lymphocytic choriomeningitis virus (LCMV), replication      39f
Lymphocytic choriomeningitis virus (LCMV), susceptibility factors      162—163
Lymphocytic choriomeningitis virus (LCMV), transcription regulation      40 41t
Lymphocytic choriomeningitis virus (LCMV), tropism and cellular receptor      32
M cell, reovirus endocytosis      15
M2; ion channel activity      45
Macrophage, lymphocytic choriomeningitis virus targeting      83—84 89
Major histocompatibility complex (MHC), antigen processing      43^44 48
Major histocompatibility complex (MHC), HLA-B57 in AIDS susceptibility      165 165t 183
Major histocompatibility complex (MHC), mouse susceptibility role      163f 164f
Major histocompatibility complex (MHC), virus modulation of class I molecule expression      43^15 87—88 121
MBP      See Myelin basic protein
MCFV      See Mink cell focus-forming virus
Mean transit time ($t_m$), measurement      18 19s
Measles virus, age effects on susceptibility      5t 167 168
Measles virus, epidemiology      127
Measles virus, genome and proteins      127
Measles virus, immunosuppression induction, discovery      82
Measles virus, immunosuppression induction, kinetics      83f 91
Measles virus, immunosuppression induction, mechanisms      91
Measles virus, P3 mimicry of corticotropin      80t
Measles virus, perpetuation      23 23t
Measles virus, persistence mechanisms      127
Measles virus, smoldering infection      See Subacute sclerosing panencephalitis
Measles virus, T cell effects      91f
MHC      See Major histocompatibility complex
Milk, shedding of viruses      22
Mims, Cedric      12
Mink cell focus-forming virus (MCFV), classification      135
Mink cell focus-forming virus (MCFV), oncogenesis      136—137
Mos, viral oncogene      134
Mouse hepatitis virus, receptors in susceptibility      162
Mucosal immune response, virus infection      67—68 68t
Mucous membrane, entry of viruses      13—15 15t
Mucous membrane, shedding of viruses      22
MuLV      See Murine leukemia virus
Murine leukemia virus (MuLV), classification      135 136t
Murine leukemia virus (MuLV), immunosuppression induction      90—91
Murine leukemia virus (MuLV), murine AIDS features      90
Murine leukemia virus (MuLV), oncogenesis, insertional mutagenesis      132—133 135—136
Murine leukemia virus (MuLV), oncogenesis, strain specificity      136
Murine leukemia virus (MuLV), susceptibility role, Fv-1      161—162
Murine leukemia virus (MuLV), susceptibility role, major histocompatibility complex associated genes      163—164
Mx, influenza susceptibility role      159—160
Mx, interferon induction      159—160
Myb, viral oncogene      134
Myelin basic protein (MBP), molecular, mimicry by viruses      79
Natural antibody, host defense      56
Natural killer (NK) cell, antibody modulation      62
Natural killer (NK) cell, cell-mediated immunopathology role      71
Natural killer (NK) cell, cytoplasmic granules      55
Natural killer (NK) cell, host defense mechanisms      55
Natural killer (NK) cell, receptors      55
Necrosis, features      45—46
Necrosis, virus induction      46
Nef, downregulation of major histocompatibility complex      44
Neural spread, comparative pathogenesis of virulent and attenuated viruses      105—106
Neural spread, viruses      20—21
Newcastle disease virus, proteolytic activation of fusion protein      32—33 33f
NK cell      See Natural killer cell
Oncogenesis, DNA viruses, adenovirus      148 -150
Oncogenesis, DNA viruses, Epstein — Barr virus      150—152
Oncogenesis, DNA viruses, human herpesvirus 8      152—154
Oncogenesis, DNA viruses, human papillomavirus      144—148
Oncogenesis, DNA viruses, tumor suppressor protein inactivation      142—144
Oncogenesis, DNA viruses, virus types      142 143t
Oncogenesis, retrovirus, accessory gene transactivation      135
Oncogenesis, retrovirus, avian leukosis-sarcoma viruses      137—138
Oncogenesis, retrovirus, cellular specificity of tumors      139—140
Oncogenesis, retrovirus, classification of viruses by mechanism      131—132 132t
Oncogenesis, retrovirus, common mechanistic themes      135
Oncogenesis, retrovirus, human T-cell lymphotrophic virus type I      135 138—139 139f
Oncogenesis, retrovirus, insertional mutagenesis by nonacute transforming viruses      132—133
Oncogenesis, retrovirus, mink cell focus-forming virus      136—137
Oncogenesis, retrovirus, molecular determinants      140s
Oncogenesis, retrovirus, multistep tumorigenesis      132 140 1401'
Oncogenesis, retrovirus, murine leukemia virus      132- 133 135—136 136t 137f
Oncogenesis, retrovirus, nonacute transforming retrovirus      133f
Oncogenesis, retrovirus, oncogenes and acute transformation      133—135 134f 134t
Oncogenesis, retrovirus, Rous sarcoma virus      137—138 138t
Oncogenesis, retrovirus, virus types      130 130t 131
Oropharynx, entry of viruses      15—16
Oropharynx, shedding of viruses      21
p53; cell cycle control      144
p53; mutations in cancer      144
p53; virus inactivation in oncogenesis      143—144 150
Panum, Peter      3
Parvovirus B19; age effects on susceptibility      166
Parvovirus B19; tropism and cellular receptor      31—32
Pasteur, L.      3
Pathogenicity      See Virulence
Persistence, cell culture models, lytic viruses      115 116t
Persistence, cell culture models, nonlytic viruses      114—115 116t
Persistence, cell culture models, variation in virus and cells      116
Persistence, diseases with persistent infection      115t 127—128 128t
Persistence, genetic determinants      116t
Persistence, herpes simplex virus      124—126
Persistence, high-titer persistent infections and immune tolerance, lytic viruses      119
Persistence, high-titer persistent infections and immune tolerance, nonlytic viruses      117—119
Persistence, human immunodeficiency virus      178
Persistence, latent infection      119—120 124—126
Persistence, measles virus      127
Persistence, mechanisms, overview      114 115t
Persistence, patterns      118f
Persistence, rules in vivo      115s
Persistence, smoldering infection persistence mechanisms, antigenic variation      121—123
Persistence, smoldering infection persistence mechanisms, cytotoxic T lymphocyte impairment      121
Persistence, smoldering infection persistence mechanisms, immune-privileged sites      120—121
Persistence, smoldering infection persistence mechanisms, infectious immune complexes      121
Persistence, smoldering infection persistence mechanisms, intercellular bridges      121 121f
Persistence, smoldering infection persistence mechanisms, major histocompatibility complex class I suppression      121
Persistence, T cell clearance      118f
Persistence, Theiler's murine enephalomyelitis virus      126
pl5E, reduction of T cell proliferation      87
Poliovirus, age effects on susceptibility      166
Poliovirus, antibody protection      197 198t
Poliovirus, eradication      197—198
Poliovirus, excretion      21f
Poliovirus, history of study      6—7
Poliovirus, inactivated virus vaccine      193 197
Poliovirus, oral polio vaccine, attenuation      9—10 100 193t
Poliovirus, oral polio vaccine, efficacy      190—192 197
Poliovirus, oral polio vaccine, safety      192—193 198
Poliovirus, oral polio vaccine, tropism      2It 190 192t
Poliovirus, pathogenesis      196f
Poliovirus, receptor expression      32t
Poliovirus, replication      39f
Poliovirus, spread      13f
Poliovirus, translational modulation      41—12
Poliovirus, tropism and cellular receptor      30—31
Poliovirus, tropism of strains      20 21
Poliovirus, vaccine development      8s 9 197
Poliovirus, viremia      18f
Poliovirus, virulence, comparative pathogenesis of virulent and attenuated viruses      105 106
Poliovirus, virulence, genetic determinants      109—111
Poliovirus, virulence, pathogenesis      196—197
Poliovirus, virulence, VP2 mimicry of acetylcholine receptor      80t
Polyoma virus, VP1 interactions with receptor      35—36
Pregnancy, virus susceptibility factor      168
Programmed cell death      See Apoptosis
Rabiesvirus, history      3 4f
Rabiesvirus, incubation period      199
Rabiesvirus, mimicry of insulin receptor      80t
Rabiesvirus, neural spread, comparative pathogenesis of virulent and attenuated viruses      105—106
Rabiesvirus, passage and virulence      106t
Rabiesvirus, pathogenesis      198—199
Rabiesvirus, spread      14f
Rabiesvirus, vaccination, CD8 cell response      200
Rabiesvirus, vaccination, immune-mediated disease enhancement      200
Rabiesvirus, vaccination, postexposure immunization      199—200 200f 200t
Rabiesvirus, vaccination, preexposure prophylaxis      199 199t
Ras, viral oncogene      134
Rb      See Retinoblastoma protein
Reed, Walter      6
Reovirus, apoptosis induction      39—40 40t
Reovirus, comparative pathogenesis of virulent and attenuated viruses      107
Reovirus, persistence      116
Reovirus, proteolytic activation      34f
Reovirus, reassortant viruses      1 lOt
Reovirus, virulence, genetic determinants      109
Replication, viral burden on host translation machinery      38
Replicon, vaccine utilization      195
Respiratory syncytial virus (RSV), cell-mediated immunopathology      73
Respiratory tract, entry of viruses      16—17 16t
Respiratory tract, shedding of viruses      21—22
Retinoblastoma protein (Rb), cell cycle control      143—144
Retinoblastoma protein (Rb), virus inactivation in oncogenesis      143—144 149
Retrovirus, definition      34
Retrovirus, genome and proteins      130 131 132f
Retrovirus, high-titer persistent infection      131
Retrovirus, integration in host genome      131
Retrovirus, oncogenesis, accessory gene transactivation      135
Retrovirus, oncogenesis, avian leukosis-sarcoma viruses      137—138
Retrovirus, oncogenesis, cellular specificity of tumors      139—140
Retrovirus, oncogenesis, classification of viruses by mechanism      131—132 132t
Retrovirus, oncogenesis, common mechanistic themes      135
Retrovirus, oncogenesis, human T-cell lymphotropic virus type 1      135 138—139 139f
Retrovirus, oncogenesis, insertional mutagenesis by nonacute transforming viruses      132—133
Retrovirus, oncogenesis, mink cell focus-forming virus      136—137
Retrovirus, oncogenesis, molecular determinants      140s
Retrovirus, oncogenesis, multistep tumorigenesis      132 140 140f
Retrovirus, oncogenesis, murine leukemia virus      132—133 135—136 136t 137f
Retrovirus, oncogenesis, nonacute transforming retrovirus      133f
Retrovirus, oncogenesis, oncogenes and acute transformation      133—135 134f 134t
Retrovirus, oncogenesis, Rous sarcoma virus      137—138 138t
Retrovirus, oncogenesis, virus types      130 130t 131
Retrovirus, replication      130—131
Retrovirus, structure      130
Retrovirus, tropism factors      34—35
Rhinovirus, temperature sensitivity      33
RNA polymerase, virus modulation      40
Rous sarcoma virus (RSV), classes      138t
Rous sarcoma virus (RSV), endogenous viruses      138
Rous sarcoma virus (RSV), history of study      7 137
Rous sarcoma virus (RSV), oncogenesis      137—138
Rous sarcoma virus (RSV), receptors      138
Rous sarcoma virus (RSV), replication-competent and defective viruses      137—138
Rous sarcoma virus (RSV), src, cellular homolog discovery      10
Rous, Peyton      7
RSV      See Respiratory syncytial virus; Rous sarcoma virus
Rubella, immunosuppression induction      92 92f
Rush, Benjamin      3
Saliva, shedding of viruses      22
Semen, shedding of viruses      22
Sendai virus, syncytium production      39
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