This issue of the journal reports regular papers. The first contribution is by Falko Dressier and discusses self-organizing mechanisms in computer networks. The second contribution is by Preetam Ghosh. Samik Ghosh, Kalyan Basu and Sajal K. Das and deals with a stochastic event based simulation technique to estimate protein-ligand docking time. The third contribution is by Morteza Analoui and Shahram Jamali and it deals with the interpretation of the Internet as a biological environment to study congestion phenomena. The fourth contribution is by Corrado Priami and it discusses how computational thinking in biology can be implemented through the use of process calculi. The last contribution is by Peter Saffrey, Ofer Margoninski, James Hetherington, Marta Varela-Rey, Sachie Yamaji, Anthony Finkelstein. David Bogle and Anne Warner and it deals with management information systems in biology. Finally we publish a corrected version of a paper by Ruet and Remy published in the previous volume of the journal.