A little over seven years have passed since the first edition was published.
During the intervening years interest in modern, instrumental LC has continued
to grow a t a high rate, surpassing the growth of interest in most other
analytical techniques. Although the basic principles of LC have not changed
there has been considerable advances in most aspects of the technique.
These advances have necessitated considerable revision of most chapters
in the first edition. Greatest changes have taken place in the areas of instrumentation,
detectors, column packings, and steric exclusion chromatography.
New chapters have been added to cover the developments in the areas of
bonded phase chromatography and the role of modern, microcomputerbased
chromatographic systems. The chapters on ion exchange and steric
exclusion have also been substantially re-written to include the latest trends
on the use of the so-called ion-pair method and bimodal columns respectively.
Throughout the book, most of the separations shown in figures have
been updated t o reflect advances in the applications of the techniques.