This book constitutes the refereed proceedings of the 10th Annual Symposium on Combinatorial Pattern Matching, CPM 99, held in Warwick, UK in July 1999. The 21 revised papers presented were carefully reviewed and selected from 26 submissions. The papers address all current issues in combinatorial pattern matching dealing with a variety of classical objects like trees, regular expressions, graphs, point sets, and arrays as well as with DNA/RNA coding, WWW issues, information retrieval, data compression, and pattern recognition.