The ICU Manual was developed as a bedside reference for house officers, fellows, and attendings who care for patients in ICUs. The book is organized in organ-specific chapters. This was done to increase the utility of and simplify the use of this manual. The organ specific approach parallels the way patients in the ICU are cared for. This approach enables the clinician to organize the diagnosis and management of complicated critically ill patients. The book has numerous illustrations, tables, and figures to ease information transfer. A variety of authors, each with their own areas of expertise, were utilized to improve the book’s perspective and overall character. We feel you will find the ICU Manual informative and helpful in your care of critically ill patients.