This book focuses on three interdependent challenges related to managing transitions toward sustainable development, namely (a) mapping sustainability for global knowledge e-networking, (b) extending the value chain of knowledge and e-networking, and (c) engaging in explorations of new methods and venues for further developing knowledge and e-networking. While each of these challenges constitutes fundamentally different types of endeavors, they are highly interconnected. Jointly, they contribute to our expansion of knowledge and its applications in support of transitions toward sustainable development.