Leaving the conventional view of chemical structure behind, these volumes demonstrate how a wealth of valuable, but hitherto unused information can be extracted from available structural data. For example, a singular structure determination does not reveal much about a reaction pathway, but a sufficiently large number of comparable structures does. The contributions authoritatively discuss the structure correlation method as well as illustrative results in detail, covering such apparently unrelated subjects as bond strength relations in solids; crystal structure prediction; reaction pathways of organic molecules; and ligand/receptor interactions and enzyme mechanisms.