Presents information on many aspects of the hazardous properties of chemical substances and correlates those properties to the functional groups, reactive sites, and other structural features in the molecules in order to aid in predicting or assessing the hazards of a compound from its structure when there is a lack of experimental data. The first part examines the four primary hazardous properties of substances in general: toxicity, carcinogenicity, flammability, and explosive characteristics. The second part details individual substances and classes of substances, including organics, metals and inorganics, industrial solvents, common gases, particulates, explosives, and radioactive substances. They are arranged, with a few exceptions, in accordance with their structures and reactive functional groups, each group beginning with a general discussion before specific compounds are considered. The second edition is substantially revised, rearranged, and enlarged to incorporate information that has emerged since 1991.