This volume of Topics in Organometallic Chemistry is a unique source that reviews the state of the art of activation of unreactive bonds both from the inorganic and from the organic synthesis perspectives. It features both stoichiometric and catalytic reactions, covering not only C-H activation, but also that of a wide range of other traditionally inert functionalities including dinitrogen. Leading experts in this field guide the reader through the wealth of new developments in these areas, which are opening up exciting opportunities for academic and industrial chemists alike. Whether you are a graduate student or a researcher in organic, inorganic or organometallic chemistry, in polymer or materials science, or in catalysis research, you will find this book an essential resource and an inspiring source of ideas for your own endeavors.