Wang (biochemistry, The Ohio State University) combines treatment of the chemistry of nitric oxide releasing substances with examples of their practical applications in biology and drug design. Coverage encompasses all classes of nitric oxide donors, from organic nitrates to nitroso compounds, guanidines, and metal-NO complexes. In addition to detailed treatment of the chemistry of NO donors, numerous examples of successful diagnostic and pharmacological applications are discussed, along with further therapeutic targets for these substances. The book is for basic scientists in NO, and for clinicians and biologists interested in the applications of NO donors.