Morse (Department of Medicine, Duke University Medical Center) presents summaries of the literature on cancer vaccines to survey the scientific background for therapeutic vaccines, the challenges to their development, and their current uses in treating cancer. Contributors examine basic issues that affect all vaccines, such as immune adjuvants and prime-boosting strategies, describe cutting-edge methods for antigen discovery, and review the preclinical development phases for each major vaccine strategy. The book will be of interest to medical oncologists and immunologists who need a synthesis of the scientific rationale, preclinical data, and clinical results for the powerful new generation of vaccines under development for the treatment of human cancers.