This book is an introduction to the science behind the new technology, and explains how the electric field interacts with the particles. It describes how these micro-systems are manufactured and how they are used to study the electrical properties of the particles. The authors offer a comprehensive treatment of the underlying principles and governing theory for the AC electrokinetic behavior of particles, review the current state of the art in AC electrokinetic manipulation and characterization of particles, and provide chapters on simulation, device design and fabrication.