Although the astrological fragments of Antigonos of Nicaea (ca. 150 CE) are often cited, especially his horoscope for the emperor Hadrian, a reliable edition and commentary have yet to appear. In addition to his astrological fragments, this volume includes the first comprehensive account of his life, work, sources, and reception. The commentary is based on a systematic appraisal of all relevant manuals and horoscopes in the ancient era.