What is the evidence that psi experiences are experienced more frequently in non-ordinary states of consciousness? David Luke addresses this question, which is beyond the scope of materialist science, with a synthesis of scientific research on anomalous experiences occurring under the influence of psychedelics from the perspective of neuroscience, psychology, parapsychology, anthropology, and transpersonal studies. This is a comprehensive exploration of chemically mediated extra ordinary human experiences, including synesthesia, extra-dimensional percepts, out-of-body-experiences, near-death experiences, entity encounter experiences, sleep paralysis, mediumship, clairvoyance, telepathy, and precognition. The author explores the implications for our understanding of consciousness and areas for further research.