Multi-core and multi-processor SoC (MPSoC) concepts started in the late 1990s, mainly to mitigate the complexity of application-specific integrated circuits (ASICs) and to bring some flexibility. The integration of instruction-set processors into ASIC design aimed both to structure the architecture and to allow for programmability. The concept was adopted for general-purpose CPU and GPU in the second phase. Among the pioneers of MPSoC design, we can list the MPA architecture from ST that used eight specific cores to implement MPEG4 in 1998. This evolved 10 years later to give rise to MPPA, the Kalray’s general-purpose MPSoC architecture. Another pioneer is the emotion engine from Sony that used five cores (two DSP and three RISC) to build the application processor for the PlayStation (PS2). This also evolved and later converged to bring the CELL architecture (developed jointly by Sony, IBM and Toshiba) in 2005. In 2000, Lucent announced Daytona (quad SPARC V8), and in 2001, Philips designed the famous Viper architecture that combined a MIPS architecture and a DSP (Trimedia). In 2004, TI introduced the OMAP architecture that combined an ARM and a DSP. Using MPSoC to build specific architectures is continuing, and almost every SoC produced today is a multi (or many) core architecture. An important evolution took place in 2005 with the ARM MPCore, the first general-purpose quad core. This was followed by several commercial, general- purpose multi-cores, including Intel Core Duo Pentium, AMD Opteron, Niagra Spark, the Cell processor (8 Cell cores + PowerPC, ring network).