Mirroring the growth and direction of science for nearly a century, the CRC Handbook of Chemistry and Physics, now in its 90th edition, adds several new tables that will be among the most accessed in the world. These include Structure and Functions of Common Drugs, Solubility Parameters of Polymers, Major World Earthquakes, and Equilibrium Constants of Selected Enzyme Reactions. It adds major updates to several more, including Threshold Limits for Airborne Contaminants, Mass Spectral Peaks of Common Organic Solvents, and Properties of the Solar System. It also adds a table of the Handbook’s greatest fans: Nobel Laureates in Chemistry and Physics.