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Isaev A. — Introduction to Mathematical Methods in Bioinformatics
 Обсудите книгу на научном форуме Нашли опечатку?Выделите ее мышкой и нажмите Ctrl+Enter Название: Introduction to Mathematical Methods in Bioinformatics Автор: Isaev A. Аннотация: Broadly speaking, Bioinformatics can be defined as a collection of mathematical, statistical and computational methods for analyzing biological sequences, that is, DNA, RNA and amino acid (protein) sequences. Numerous projects for sequencing the DNA of particular organisms constantly supply new amounts of data on an astronomical scale, and it would not be realistic to expect that biologists will ever be able to make sense of it without resorting to help from more quantitative disciplines. Many studies in molecular biology require performing specific computational procedures on given sequence data, for example, simply organizing the data conveniently, and therefore analysis of biological sequences is often viewed as part of computational science. As a result, bioinformatics is frequently confused with computational sequence analysis, which is somewhat narrower. However, understanding biological sequences now increasingly requires profound ideas beyond computational science, specifically, mathematical and statistical ideas. For example, the protein folding problem incorporates serious differential geometry and topology; understanding the evolution of sequences is dependent upon developing better probabilistic evolutionary models; analysis of microarray data requires new statistical approaches. Generally, when one goes beyond algorithms and starts either looking for first principles behind certain biological processes (which is an extremely difficult task) or paying more attention to modeling (which is a more standard approach), one crosses the boundary between computational science and mathematics/statistics. These days many mathematicians are becoming interested in bioinformatics and beginning to contribute to research in biology. This is also my personal story: I am a pure mathematician specializing in several complex variables, but now I work in bioinformatics as well Язык: Рубрика: Разное/ Статус предметного указателя: Неизвестно ed2k: ed2k stats Год издания: 2006 Количество страниц: 303 Добавлена в каталог: 21.04.2018 Операции: Положить на полку | Скопировать ссылку для форума | Скопировать ID
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