This two-volume set LNCS 4277/4278 constitutes the refereed proceedings of 14 international workshops held as part of OTM 2006 in Montpellier, France in October/November 2006.

The 191 revised full papers presented were carefully reviewed and selected from a total of 493 submissions to the workshops. The first volume begins with 26 additional revised short or poster papers of the OTM 2006 main conferences. Topics of the workshop papers contained are agents, Web services and ontologies merging (AWeSOMe 2006), community informatics (COMINF 2006), information security (IS 2006), knowledge systems in bioinformatics (KSinBIT 2006), modeling inter-organizational systems, focusing on collaboration and interoperability, architectures and ontologies (MIOS-CIAO 2006), mobile and networking technologies for social applications (MONET 2006), ontology content and evaluation in enterprise (OnToContent 2006), object-role modeling (ORM 2006), pervasive systems (PerSys 2006), a PHD symposium (OTM 2006 Academy Doctoral Consortium), reliability in decentralized distributed systems (RDDS 2006), semantic-based geographical information systems (SeBGIS 2006), and Web Semantics (SWWS 2006).