The third of four volumes discusses the role of ubiquitin-mediated protein breakdown in cellular regulation and physiology. Required reading for molecular biologists, cell biologists and physiologists with an interest in the topic.Content:
Chapter 1 Ubiquitin: A New Player in the Peroxisome Field (pages 1–20): Astrid Kragt, Rob Benne and Ben Distel
Chapter 2 The Ubiquitin Proteasome System and Muscle Development (pages 21–47): Johnny Kim and Thorsten Hoppe
Chapter 3 The COP9 Signalosome: Structural and Biochemical Conservation and Its Roles in the Regulation of Plant Development (pages 48–75): Vicente Rubio and Xing Wang Deng
Chapter 4 Ubiquitin and Protein Sorting to the Lysosome (pages 76–102): John McCullough, Michael J. Clague and Sylvie Urbe
Chapter 5 ISG15?dependent Regulation (pages 103–131): Arthur L. Haas
Chapter 6 The Role of the Ubiquitin–Proteasome Pathway in the Regulation of the Cellular Hypoxia Response (pages 132–148): Koh Nakayama and Ze'ev Ronai
Chapter 7 p97 and Ubiquitin: A Complex Story (pages 149–193): Louise C. Briggs, Ingrid Dreveny, Valerie E. Pye, Fabienne Beuron, Ciaran F. McKeown, Xiaodong Zhang and Paul S. Freemont
Chapter 8 Cdc48 (p97) and Its Cofactors (pages 194–211): Alexander Buchberger
Chapter 9 Deubiquitinating Enzymes, Cell Proliferation, and Cancer (pages 212–231): Rohan T. Baker