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Название: Protein Acetylation: Methods and Protocols
Авторы: Hake S., Janzen C.
The addition of chemical tags to proteins has long been recognized as one important mechanism to regulate different functions of the target protein. Of particular interest is the
enzymatic addition of one acetyl group to proteins, a reversible process that has been discovered more than 40 years ago, and which can occur co- and posttranslationally. Highly
speci fi c acetyltransferases catalyze the addition of an acetyl group to target sequences in
proteins, and deacetylases speci fi cally remove these chemical tags if necessary.