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                    | Hermanson G.T. — Bioconjugate Techniques |  
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                    | Предметный указатель |  
                    | | Louis      208 Low-density lipoprotein      see “LDL”
 Lowe      49 51 139 177 178 209 226 647 659
 lu      279
 Lubin      207 208
 Lucifer Yellow      355 357 358
 Lucifer Yellow iodoacetamide, general description and use      359
 Lucifer Yellow, comparison to Cascade Blue      354
 Lucifer Yellow, general description and use      358 361
 Lucifer Yellow, Lucifer Yellow CH      354
 Luduena      227
 Ludwig      173 204
 Luminescence      298 300 301 584 668
 Luminol      634
 Lumper      209 211
 Lundbald      110
 Luteinizing hormone b mRNA      396
 Lymphoblast receptors      201
 Lymphocytes      198 260 377
 Lymphocytes, B cells      419 420
 Lymphocytes, receptors      296
 Lymphocytes, T cells      419 420
 Lymphocytes, T-helper cells      419
 Lymphokines      420
 Lymphokines, conjugates with antibodies      494
 Lymphokines, conjugation to toxins      517
 Lymphotoxin      200
 Lysine      6 91 98 105 187 394 398 473 570
 Lysine for biocytin      287 392
 Lysine for constructing trifunctional cross-linkers      287
 Lysine for MAP      428
 Lysine for quenching glutaraldehyde reactions      471 472 583
 Lysine, blocking of      126
 Lysine, detection with TNBS      112
 Lysine, pKa      7
 Lysine, reaction with anhydrides      146
 Lysine, reaction with glutaraldehyde      119
 Lysine, reaction with haloacetyl compounds      147
 Lysozyme      153 183 286 614
 m-Maleimidobenzoyl-N-hydroxysuccinimide ester      see “MBS”
 m-Maleimidobenzoyl-N-hydroxysulfosuccinimide ester      see “Sulfo-MBS”
 Machy      549 553
 Macrophages      549
 Magic bullet      494
 Magnesium      632 640
 Mahan      236
 Major histocompatibility complex      see “MHC”
 Malachite green, similarity to rhodamine      300
 Malcolm      46 654
 Male      420
 Maleamic acid      148 235 440
 Maleic acid      94 129
 Maleic acid imides      see “Maleimides”
 Maleic anhydride      148
 Maleic anhydride as a reversible blocking agent      127 129
 Maleic anhydride, 2-methyl derivative      96 128
 Maleic anhydride, deblocking of acylated amines      95
 Maleic anhydride, general description and use      94
 Maleimide      24 95 96 276 307 311 423 461 483 504 542 565 576
 Maleimide in biotinylation reagents      384
 Maleimide in carbonyl and sulfhydryl reactive cross-linkers      249
 Maleimide of
  250 Maleimide of benzophenone-4-maleimide      281
 Maleimide of biotin-BMCC      384
 Maleimide of BMH      210
 Maleimide of fluorescein-5-maleimide      309
 Maleimide of GMBS      243
 Maleimide of MBS      237 522 546
 Maleimide of MPBH      249
 Maleimide of NEM      130
 Maleimide of SMCC      519
 Maleimide of SMPB      242 524
 Maleimide, absorptivity of      441
 Maleimide, derivative of Jeffamine      618
 Maleimide, dextran-modified      628
 Maleimide, hydrolysis of      148 440
 Maleimide, reaction of      148 235
 Maleimide, relative stability      228
 Maleimide, stability of in SMCC      236
 Maleimide, stability of in sulfo-SMCC      440
 Maleimide, use in immunotoxin conjugation      516
 Maleylation      94
 Malhotra      654
 Malignant      298 490 494
 Mallett      559
 Mallia      86 121
 Malondialdehyde      215
 Malonic acid      165
 Malonic acid, formed through diazopyruvate photolysis      272
 Manabe      494 525
 Manak      641 666
 Mandy      208
 Mannich reaction      161 162 216 473
 Mannich reaction in hapten-carrier conjugation      449
 Mannich reaction with tyrosine      12
 Mannich reaction, general description      450
 Mannik      473
 Mannose      20 27 36
 Mannose, binding of ricin A chain      500
 Mannose, reaction with phenylhydrazine      32
 Manshouri      614
 Manske      501
 MAP      428
 Marcholonis      410
 Marcus      177
 Marfey      212
 Marinetti      282
 Markwell      208 405 409
 Martin      239 242 243 524 533 543 544 545 559 566
 Martinez-Ramon      600
 Maruyama      153
 Marwell      408
 Masamune      88
 Massague      260
 Masuho      499 516
 Matheson      36
 Matteucci      93
 Matthay      494 552
 Matthews      49
 Mattiasson      473
 Mayhew      532
 Mazaitis      403
 MBS      148 245 440
 MBS in coupling antibodies to liposomes      553
 MBS, activation of PE using      546
 MBS, activation of ricin using      522
 MBS, analog of      239
 MBS, general description and use      237
 MBS, immunotoxin preparation using      522
 MBS, liposome conjugation using      542
 MBS, maleimide stability      238
 MBS, use in antibody—enzyme conjugation      461
 MBS-DPPE      546
 McBroom      447
 McCleary      36
 McGinnis      36
 McGown      302 320
 McInnes      396
 McKinney      304
 Means      21
 Meares      365 367
 Megathura crenulata      422
 Meige      328
 Meighen      92
 Meijer      255
 Meinhoffer      143 212
 Melcher      633
 Mengo virion      193
 Mentzer      205 207 208
 Mercaptans      85
 
 | Mercaptosuccinic acid      327 Mercuration, of pyrimidines      46
 Merrifield      178
 MES      171
 Messenger RNA      41
 Messer      633
 Metal chelate affinity chromatography      484 486
 Metal chelators      632
 Metal ions      365
 Metals, immobilized      486
 Metasticies      490
 Methanol      216 309 531 544 546 633
 Methionine      5 90 98 105
 Methionine, reaction with haloacetyl compounds      147
 Metho p-toluene sulfonate      46 177
 Methyl 3-mercaptopropionimidate hydrochloride      57
 Methyl 4-mercaptobutyrimidate      see “2-Iminothiolane”
 Methylene chloride      409
 Methylhydroxylamine      646
 Metrizamide      532
 Metz      177
 Meurling      365 495
 Meyne      670
 MHC      419
 Mice      425
 Micelle-chelate      369
 Micelles      529
 Micelles, inverted      530
 Microinjection      359
 Microplate      223
 Microscopy      206
 Microscopy, electron      593
 Microscopy, fluorescence      584
 Microscopy, light      593
 Microscopy, use of avidin-biotin interaction      574
 Microsomes      207
 microtubules      308 322 324
 Mikkelsen      214
 Millar      201
 Miller      239
 Miron      612 614
 Miskimins      75
 Mitchison      322
 Mitochondria      324
 Mitomycin-C      624
 Mitotic spindle assembly      322
 Mittal      328
 Mixed disulfide      77 80 88 150 151 152
 Miyakawa      208
 MLV      427
 Modeccin      497 498
 Modeccin, structure of      497
 Moeremans      594
 Moffatt oxidation, of mPEG      618
 Moi      368
 Mollusk      422
 Momordica charantia seeds      497
 Momordin      497
 Mono      98
 Mono-iodotyrosine      402
 Monocarboxymethyllysine      147
 Monoclonal antibodies      456
 Monoclonal antibodies, activity loss of      456
 Monoclonal antibodies, conjugation with toxins      494 496
 Monoclonal antibodies, humanized mouse      496
 Monoclonal antibodies, produced from hapten-carrier conjugates      421
 Monoclonal antibodies, recombinant      496
 Monomethoxypolyethylene glycol      see “mPEG”
 Monooxygenase      208
 Monosaccharides, cyclic forms      27
 Monosaccharides, functional groups      28
 Monosaccharides, stereoisomers      28
 Monsan      218 453
 Montesano      195
 Moore      209 210
 Morales      308 310
 Moreland      278
 Morgan      195 331
 Moroi      194 266
 Moroney      209 211 501
 Morris      597 602 603
 Morrison      258 410 670
 Mosbach      178 323 325
 Mossberg      319 325 330
 Motta-Hennessy      370
 Moudrianokis      206
 Mouse IgG2a      479
 Mouse, IgG1      479
 MPB-DPPE      552
 MPBH, general description and use      249
 MPB—PE      544
 MPEG      607 (see also “PEG”)
 mPEG, activation with CDI      615 616
 mPEG, activation with DSC      612
 mPEG, activation with trichloro-s-triazine      608
 mPEG, aldehyde derivative of      618
 mPEG, anhydride modification of      609
 mPEG, chloroformate derivative of      611
 mPEG, modification with succinic anhydride      614
 mPEG, Moffatt oxidation of      618
 mPEG, succinimidyl carbonate derivative of      611
 mPEG, succinylation of      611
 mRNA      41 338 395
 Muckerheide      102 423 424 550
 Muckerheide, mucoproteins      20 36
 Mudd      208
 Mukkala      369
 Muller-Eberhard      525
 Mullis      640
 Multilamellar vesicles      530 (see also “MLV”)
 Multiple antigenic peptide      see “MAP”
 Mumtaz      607 620
 Muramoto      304
 Muramyl dipeptide      550
 Murayama      221
 Murphy      328
 Murray      133
 Mustards      147
 Mustards, reactions of      226
 Mutter      618
 Myelin      212
 Myers      239 243 500 517 522 524
 Myoglobin      422
 myosin      308 389
 Myosin light chains      328
 Myosin subfragment      1 208
 Myristic acid      536
 N'-[5-[[4-[[5-(Acetylhydroxyamino)pentyl]-amino]-l,4-dioxobutyl]hydroxyamino]-pentyl]-N-(5-amino-pentyl)-N-hydroxybutanediamide      see “DFA”
 N,N'-o-Phenylenedimaleimide      236
 N,N'-oxydimethylenedimaleimide      236
 N,N’-carbonyldiimidazole      101 see
 N,N’-dimethylcasein      394
 N,N’-Disuccinimidyl carbonate      156 see
 N-(
  -Iodoethyl) trifluoroacetamide      see “Aminoethyl-8” N-(4,4-Difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacene-3-propionyl)-N’-iodo-acetylethylenediamine      see “BODIPY FLIA”
 N-(4,4-Difluoro-5,7-diphenyl-4-bora-3a,4a-diaza-s-indacene-3-propionyl)-N’-iodoace-tylethenediamine      see “BODIPY 530/550 IA”
 N-(4-Aminobutyl)-N-ethylisoluminol      670
 N-(4-Azido-2-nitrophenyl)-aminopropyl-N'-(N-d-biotinyl-3-aminopropyl)-N'-methyl-l,3-propanediamine      see “Photobiotin”
 N-(4-Azidophenyl)thiophthalimide      278
 N-(7-Maleimidobutyryl-oxy)succinimide ester      see “GMBS”
 N-(7-Maleimidobutyryloxy)sulfosuccinimide ester      see “Sulfo-GMBS”
 N-5-Azido-2-nitrobenzoyl-oxysuccinimide      see “ANB-NOS”
 N-Acetyl homocysteine thiolactone, general description and use      68
 N-Acetyl homocysteine thiolactone, immobilization of      86
 N-Acetyl-D-galactosamine      27 108
 N-Acetyl-D-galactose, oxidation with galactose oxidase      116 158
 N-Acetyl-D-glucosamine      27 34 36
 N-Acetylneuraminic acid      27
 N-acylimidazole      154 155 183
 N-acylimidazole, hydrolysis of      185
 
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