This book covers solution chemistry of iron in biological media, the importance of iron for biological systems, iron uptake in plants, yeasts, and mammals, intracellular iron storage, and iron absorption in mammals, especially humans. Other subjects are the pathophysiology of iron deficiency and overload in humans, iron and infection, and iron and oxidative stress. The book is of interest to researchers in biochemistry, molecular biology, cell biology, and the medical sciences. This second edition takes into account breakthroughs in the field since 1991 due to the application of molecular biological techniques to cellular biology of iron metabolism. This edition includes color illustrations, and a new chapter on the interactions of iron with other metals, particularly copper and zinc.