The aim of the inaugural meeting of the Sant Cugat Forum on Astrophysics was to address, in a global context, the current understanding of and challenges in high-energy emissions from isolated and non-isolated neutron stars, and to confront the theoretical picture with observations of both the Fermi satellite and the currently operating ground-based Cherenkov telescopes. Participants have also discussed the prospects for possible observations with planned instruments across the multi-wavelength spectrum (e.g. SKA, LOFAR, E-VLT, IXO, CTA) and how they will impact our theoretical understanding of these systems.In keeping with the goals of the Forum, this book not only represents the proceedings of the meeting, but also a reflection on the state-of-the-art in the topic.