A laboratory guide to current cytokine research methodology, focusing on cell biology techniques for studying cytokines, cytokine receptors, and cytokine driven processes. Chapters cover areas including human B- cell responses to cytokines, T cells and cytokines, the generation and quantitation of cell-mediated cytotoxicity, cytokine regulation of endothelial cells, assays for leucocyte migration, flow cytometric detection of intracellular cytokines, development of antibodies to cytokines, and quantitative biological assays. This third edition contains new information reflecting progress in the field since 1995. Balkwill is affiliated with St. Bartholomews and the Royal London Hospital School of Medicine and Dentistry.