This volume presents the proceedings of the 5th Conference on Artificial Intelligence in Medicine Europe, AIME '95, held in Pavia, Italy in June 1995. The volume contains 32 full refereed selected papers contributed by researchers and professionals coming from computer science departments, medical informatics departments, and hospitals; in addition there are the keynote address and 28 poster presentations. The volume is organized in topical sections on medical records, temporal reasoning and simulation, probabilistic models, patient management and therapy planning, evaluation of knowledge-based systems, diagnostic support systems, models for clinical information systems, and neural networks and image interpretation.