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Автор: Nagata S.
G-CSF is a 20-25 kDa glycoprotein that specifically regulates the production of neutrophilic G granulocytes as well as enhancing the functional activities of mature neutrophils. It is produced by activated macrophages, endothelial cells, and fibroblasts. G-CSF is widely used clinically in the treatment of patients with neutropenia after cancer chemotherapy.