Comprises 22 contributions which provide an overview of the role of cytokines in interactions between neuroendocrine and immune systems and the clinical implications of these interactions. Topics include all the cytokines< — >interleukins, interferons, enkephalins, and endorphins< — >with an emphasis on immune, central nervous, and endocrine systems. Representative topics include: the role of cytokines in depression and immunity; neuroendocrine regulation of the immune process; opioid systems; and the control of pain in peripheral tissues by cytokines and neuropeptides. Of interest to basic researchers and clinicians in the field.