Volume thirty-nine in the internationally acclaimed Advances in Clinical Chemistry, contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics ranging from basic biochemical exploration to cutting edge microarray technology. In keeping with the tradition of the series, this volume emphasizes novel laboratory advances with application not only to both clinical laboratory diagnostics, but as well as practical basic science studies. This volume of Advances in Clinical Chemistry is an indispensable resource and practical guide for twenty-first century practitioners of clinical chemistry, molecular diagnostics, pathology, and clinical laboratory sciences in general. *Presents advances in assay methods such as immuno-PCR technology and proteomic assessment*Discusses the development and potential applications of novel biomarkers of chronic conditions (i.e,. Alzheimer's disease, cancer, cardiovascular disease and depression)*Addresses molecular and biochemical findings in the aging process