This book constitutes the refereed proceedings of the 4th International Conference on Grid and Cooperative Computing, GCC 2005, in Beijing, China in November/December 2005.

The 57 revised full papers and 84 revised short papers presented together with 2 invited talks were carefully reviewed and selected from a total of 576 submissions. The papers are organized in topical sections on grid service and grid security, grid middleware and applications, knowledge grid and semantic grid, resource management, P2P computing and automatic computing, performance evaluation and modeling, and software engineering and cooperative computing.