Biological Chemistry is defined as the chemistry of the compounds and processes that constitute livingorganisms. The ultimate goal, of course, is to understand and define biology at a mechanistic level. This was aptly stated in an historical treatise on the founding of the Journal of Biological Chemistry, where John Edsall quoted a statement in a letter from J. L. Loeb (in Berkeley), The future of biology lies with those who attack its problems from a chemical point of view. What was an emerging field in 1900 with its origins in physiology, nutrition and chemistry has broadened and expanded to include numerous other fields including mechanistic enzymology, molecular biology, structural biology, cell biology, genomics, proteomics, bioinformatics, metabolomics and others, thatwere not defined as discrete fields at that time.