The books (LNCS 6088 and 6089) constitute the refereed proceedings of the 7th European Semantic Web Conference, ESWC 2010, held in Heraklion, Crete, Greece, in May/June 2010. The 52 revised full papers of the research track presented together with 10 PhD symposium papers and 17 demo papers were carefully reviewed and selected from more than 245 submissions. The papers are organized in topical sections on mobility track, ontologies and reasoning track, semantic web in use track, sensor networks track (part I), and services and software track, social web track, web of data track, demo and poster track, PhD symposium (part II).