This book constitutes the refereed proceedings of the 19th International Conference on Computer Safety, Reliability, and Security, SAFECOMP 2000, held in Rotterdam, The Netherlands in October 2000. The 33 revised full papers presented together with three invited papers were carefully reviewed and selected for inclusion in the book. The papers are organized in topical sections on verification and validation; software process improvement; formal methods; safety guidelines, standards and certification; hardware aspects; safety assessment; design for safety; and transport and infrastructure.