This book constitutes the refeered proceedings of the 19th International Conference on Information Processing in Medical Imaging, IPMI 2005, held in Glenwood Springs, Colorado, in July 2005.

The 63 revised full papers presented were carefully reviewed and selected from 245 submissions. The papers are organized in topical sections on shape and population modeling, diffusion tensor imaging and functional magnetic resonance, segmentation and filtering, small animal imaging, surfaces and segmentation, applications, image registration, registration and segmentation.