This book constitutes the refereed proceedings of the Second Brazilian Symposium on Bioinformatics, BSB 2007, held in Angra dos Reis, Brazil, in August 2007; co-located with IWGD 2007, the International Workshop on Genomic Databases.

The 13 revised full papers and 6 revised extended abstracts were carefully reviewed and selected from 60 submissions. The papers address a broad range of current topics in computationl biology and bioinformatics featuring original research in computer science, mathematics and statistics as well as in molecular biology, biochemistry, genetics, medicine, microbiology and other life sciences.