is the most comprehensive reference guide on the syntheses of LSD-25. Reactions are described including a review of the Task Force Report: Narcotics and Drug Abuse, Annotations and Consultants' Papers. Many of the reactions include: Synthesis of N,N-dialkyl substututed lysergamides. The Curtis Reaction. Preparation of d-iso-lysergic acid hydrazide; d-iso-lysergic acid azide; d-iso-LSD.
The Garbrecht Synthesis. Epimerization of d-iso-LSD into d-LSD. Fractional crystallization of LSD-25. Separation of d-lysergamides from d-iso-lysergamides. Alternative syntheses of lysergamides. Ergoline alkaloids from Rivea Corymbosa; morning glories; Argyreia nervosa. Life history and poisonus properties of Claviceps paspali. Host plants to Claviceps paspali. Host plants resistant to artificial inoculation of Claviceps paspali. Developing Claviceps purpurea. Claviceps purpurea cultivation and strain selection. Preparation of media. Inoculation of cultures. Alkaloid production by Claviceps cultures. More fermentations. Alkaloid extraction from cultures. Recrystallization of lysergic acid. Lysergic acid from Claviceps culture. Field inoculation of rye with Claviceps purpurea. Preparation of ethylamine and diethylamine. Preparation of ethyl bromide. Preparation of hydrazine sulfate and anhydrous hydrazine. Tablet manufacture. Molded tablets. Tablet machine. Compressed tablets. Preparation of ''Clearlight'' Carrier: ''sheeting''. Blotter carrier. N,N-Dialkyltryptamines and substituted alpha-alkyl and N,N-dialkyltryptamines. Psilocin from psilocybin containing mushrooms. Increasing psilocybin & psilocin content of cultivated mushrooms using tryptamine. Preparation of N,N-dialkyltryptamines. Preparation of tryptamine from tryptophan. Preparation of alpha, alpha-dialkyltryptamines. Electrolytic reduction of 3-(2-nitro-vinyl)indole to prepare tryptamine. Syntheses of gramine and analogs. Alternative syntheses of tryptamines. Preparation of substituted indoles. Melatonin. Adrenoglomerulotropin. Harman; harmaline; harmalol; harmine; harmol. Neurotoxic tryptamines. Future research. Over 225 references to scientific and medical journal articles. Indexed.