Recent breakthroughs in recombinant DNA technology and the availability of sophisticated equipment accessible to almost any laboratory, have contributed to the development and perfection of powerful hybridization tools. Recently, nucleic acid hybridization has not only become a cornerstone in molecular biology research but also a powerful supplement to other diagnostic tools. These diagnostic methods are set out in a logical and clear two-part work in this "Laboratory Techniques" series. The volume is divided into theory and preparation (Part I), and probe labelling and hybridization techniques (Part II).