In this expanded fourth edition of his popular textbook, John Smith once again demystifies biotechnology — especially genetic manipulation — by clearly and accessibly explaining the history, techniques, and applications of modern biotechnology for students and the general reader. All aspects of biotechnology are covered, and a positive stance is taken concerning the potential benefits to human society. Greater emphasis is also given to the public perception of biotechnology and the ethical and safety questions raised. The book is ideal for short introductory biotechnology courses at the university level.