This book constitutes the proceedings of the 11th International Conference on Middleware, held in Bangalore, India, during November 29 - December 3, 2010. The 19 papers presented have been carefully reviewed and selected from 116 submissions. The papers are organized in topical sections on cloud computing; data management; publish-subscribe and multicast systems; social and location-aware middleware; reliability and legacy; trust and security; and transactional memory.