Features cutting-edge protocols for generating and maintaining genetically modified murine stains and includes techniques for cloning, conditional transgenesis, and cryopreservation of germlines. Emphasis is on manipulation of the mammalian genome.

"It will provide a valuable source of information. It will also remind you of the enormous potential that transgenesis has to offer the biologist. Transgenic research will underpin many future applications from evaluating viral vectors for gene therapy and vaccination to bioreactors for the production of proteins, from models of disease to screening tools for biological activity, from genome mapping to gene function. This book details protocols to let you participate in this." -Cloning and Stem Cells

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