Volume 100 of Advances in Heterocyclic Chemistry commences with a chapter by C. A. Ramsden (University of Keele, UK) on 1,2-benzoquinones as a precursor of a wide variety of heterocycles. Catherine L. Lucas and C. J. Moody (University of Nottingham, UK) provide a summary of naturally occurring 1,4-thiazines, a compound class that has been extensively investigated recently; much information on the synthesis and properties of important derivatives is included.
S. A. Raw (AstraZeneca, UK) and R. J. K. Taylor (University of York, UK) describe novel developments in the preparation and applications of 1,2,4-triazines, especially inverse electron demand Diels–Alder reactions. Heteroaryl radicals, with particular emphasis on pyridyl, indolyl, and thienyl radicals, in which the unpaired electron occupies an sp2 orbital orthogonal to the p-system are covered by D. Mirizzi and K. Jones (Institute of Cancer Research, London, UK) and S. T. Hilton (School of Pharmacy, University of London, UK).
B. Stanovnik and U. Grosˇelj (University of Ljubljana, Slovenia) review applications of acetone-1,3-dicarboxylates in heterocyclic synthesis with emphasis on pyrazole- and pyrimidine-derived ring systems. A. P. Sadimenko (University of Fort Hare, South Africa) reports on some of the remarkable advances in organometallic chemistry of heterocycles, which have occurred in the last decade.
The final chapter in this volume by G. Jones (University of Keele, UK) and B. Abarca (Universidad de Valencia, Spain) updates the chemistry of [1,2,3]triazolo[1,5-a]pyridines for the period 2001–2009.